Phlebotomy Essentials
6th Edition
ISBN: 9781451194524
Author: Ruth McCall, Cathee M. Tankersley MT(ASCP)
Publisher: JONES+BARTLETT PUBLISHERS, INC.
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Women with urinary tract infections caused by E. coli are generally treated with a course of antibiotics. A common complication of the antibiotic treatment is the occurrence of a vaginal yeast infection caused by Candida albicans, an organism that is normally present in very low numbers in the human vaginal tract. This complication occurs because:
- The E. coli infection damages the reproductive epithelium, causing a breach in the tight junctions and allowing invasion by the Candida albicans.
- The E. coli infection induces adhesion molecule expression on the reproductive epithelium, allowing attachment of the yeast.
- The antibiotic treatment kills all strains of fungi present in the reproductive tract, except the Candida albicans.
- The E. coli infection causes gastrointestinal distress leading to diarrhea.
- The antibiotics kill many of the commensal organisms in the reproductive tract, allowing overgrowth of the
fungus .
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