Why would a a pure protein screening approach be used to discover a small molecule inhibitor of a Kinesin instead of other methods?  What is one advantage and one disadvantage of pure protein screens?

Q: Which term is incorrectly matched?(a) biogeochemical cycles—recycling of life-essential ele-ments…

A: The presence of all physical surroundings on Earth are known as the environment. The environment…

Q: Explain the methodology, rationale, and challenges in the control of Triatomine vectors.

A: Triatomine: Triatominae bugs are the vectors of Chagas disease. These belong to the Reduviidae…

Q: How can the binding assay approach be utilized to match coding triplets with their amino acid…

A: Live cells use the genetic code to turn information encoded in genetic material (DNA or mRNA codon…

Q: Disorders associated with and epigenetic defect resulting in decreased protein expression should be…

A: The use of molecular tests for diagnosing disorders associated with epigenetic defects resulting in…

Q: Fluorescent Protein-Based Biosensors and Their Clinical Applications

A: Green fluorescent protein and its common proteins have shed light on many biological problems. The…

Q: Describe the Meselson and Stahl experiment and outline its significance.

A: Meselson and Stahl's experiment was done to demonstrate the semi-conservative nature of DNA…

Q: What are DNA probes

A: When two single-stranded DNA or single-stranded RNA molecules are allowed to be together and form…

Q: Given these options, which best describes the Cre-Lox system A) can be applied to control the…

A: The Cre-lox system is one of the most powerful and versatile tools developed for mouse genetics. It…

Q: All of the following are true about the design of the Beadle and Tatum experiment (one gene one…

A: The "one gene, one enzyme" theory was supported by George Beadle and Edward Tatum's demonstration…

Q: Why are appropriate transducer orientation and image standardization important in vascular…

A: Importance of transducer orientation in Vascular Sonography: *In order to get an exact image, the…

Q: What is a CT value and what is its importance in interpreting gene expression?

A: Using technology in biology has changed the way we understand living things and has opened up new…

Q: How does high throughput screening work?

A: High-throughput screening (HTS) is a automated process to test large numbers compounds (chemical or…

Q: What is high throughput screening used for?

A: High throughput screening:   It is a scientific method of drug discovery. With the use of robotics,…

Q: Design a diagnostic test kit based on bio-sensor principles, for COVID-19. (Specify the main…

A: Introduction :- Covid-19 is a very contagious infection ( disease) caused by the SARS-CoV-2. It…

Q: Based on the NCBI Blastp and reciprocal analysis, are there any mutations to suggest that mus…

A: In thе contеxt of tеsting thе human FGFR3 gеnе in Mus musculus, NCBI Blastp and rеciprocal analysis…

Q: Why is the DNS method used in glucose assay?

A: 3,5-dinitrosalicylic acid (DNS) measure has been broadly utilized for the estimation of diminishing…

Q: What is meant by the term genetic testing? How do testing at theprotein level and testing at the DNA…

A: Medical genetics is one of the branches of medicine, which involves the management and diagnosis of…

Q: Explain ORF analysis.

A: Protein translocation is a process where proteins move between cellular components. It can occur…

Q: What does MEGA stand for and what is this assay used to determine? How to do perform the assay?

A: Many assisted reproductive techniques are widely used around the globe.

Q: Beadle and Tatum removed arginine and other substances from the nutrient medium of the mutated…

A: Beadle and Tatum experimentally proved the "one gene one enzyme" hypothesis. They took wild-type…

Q: phenotypic screens.

A: Phenotype: Any measurable characteristic or distinctive trait possessed by an organism is called The…

Q: How do you see regulatory frameworks evolving to address these sophisticated types of collusion and…

A: Currently, regulatory frameworks in health science are primarily focused on ensuring the safety and…

Q: What are the best methods for isolation of plasma membrane (PM) proteins from mammalian cells?

A: Mammalian cells are the eukaryotic cells obtained from a mammal such as a human. Cells can be from…

Q: Design a diagnostic test kit based on bio-sensor principles, for COVID-19. (Specify the main…

A: Biosensors are important devices that help in detecting any viruses. It provides the qualitative and…

Q: How would you determine the concentration of a protein that falls outside (above or below) the…

A: Introduction A biomolecule, sometimes known as a biological molecule, is any of the various…

Q: Quantitatively describe the unique focusing capability of IEF and identify factors that increase…

A: IEF stands for isoelectric focusing which is a technique used to resolve a mixture of proteins on a…

Q: How can genetic testing help in cancer diagnosis? Briefly explain

A: Cancer is a group of disease which involves abnormal growth of cell with the ability to spread to…

Q: Why is the bradford assay method using BSA sensitive ? and how does it compare to the amino acid…

A: Bradford assay: It is a widely used method for measuring total protein concentration and different…

Q: design

A: Depending on the method of ingestion anticipated for their therapeutic effect, medications are…

Q: Describe the rationale behind the electrophoretic mobility shift assay.

A: Nucleic acid is serving as primary information carrying molecule in cells. There are two types of…

Q: Explain why an investigator might want to create aconditional knockout mouse.

A: A conditional Knockout mouse defines an animal model in which a gene of interest can be: inactivated…

Q: Genetic engineering and gene therapy are similar fields within genomics. What do they have in common…

A: Genetic engineering and gene therapy are similar fields with genomics. They are both similar as they…

Q: Why is it necessary to examine gene-expression profiles, in additionto genome sequences, for…

A: Gene expression profiling is the analysis of the behaviour of thousands of genes at once to…

Microbial Isolation

Isolation of the microorganisms in microbiology is the process of developing a pure culture by separating one species of microbe from a mixture of many other species. A pure culture is a culture that contains only one species of microbe.