Which of the following would restore a gene back to its proper reading frame? A. one insertion that contained 3 nucleotides   B. three insertions that contained two nucleotides each   C. one deletion of 2 nucleotides and one insertion of 3 nucleotides.   D. two insertions that contained one nucleotide each

Identify the best match between the mutation description and term.   a. Transversion: results in a change in single nucleotide from a purine to another purine or a pyrimidine to another pyrimidine   b. Nonsense mutation: a change in the DNA that changes the codon code from one amino acid to another amino acid   c. Missense mutation: causes a drastic change in phenotype because the change causes a premature stop in the amino acid sequence   d. Indel: has the potential to cause large changes in transcription and subsequence amino acid sequence due to reading frameshifts

Sickle cell anemia is an example of a genetic disease caused by a point mutation. To answer this question look at the information in chapter 3 of the OpenStax book. If you use another resource that is fine but you will need to share the link. a. Describe the specific change in the nucleotide sequence sequence from normal to mutated hemoglobin. b. Describe the specific change in the amino acid sequence from normal to mutated hemoglobin. c. Explain the structural effect that this point mutation has on the hemoglobin protein. d. Explain how this mutation affects the function of the hemoglobin protein.

HindIII is a restriction endonuclease that recognizes a palindrome sequence. Predict which one is the HindIII recognition site: a. AAGGTT b. AAGCTT c. AGCCGA d. AGCGCA e. AGCAGC