Which of the following statements about GTP and GTPases is correct? 1. GTPase activating protein (GAP) binds to GTPase when it is in the active state. 2. The exchange factor GEF binds GTP directly and delivers it to the GTPase. 3. The "switching" behaviour of GTPase is because GTP hydrolysis causes the enzyme to change shape. 4. Structural differences in the terminal phosphate group explains why ATP hydrolysis releases

Some proteins may be phosphorylated by enzymes called kinases. Which of the following statements best describes this type of post-translational modification (PTM)? Phosphorylation is an irreversible modification of an amino acid side chain in the protein. Phosphorylation is a reversible modification of an amino acid side chain in the protein. Phosphorylation is an irreversible modification of the peptide backbone. Phosphorylation is a reversible modification of the peptide backbone.

What are some of the interactions made between ATP and the kinase? Describe bonds that the protein makes with each of the following: the phosphate groups the sugar the adenine base

In the normal cycle of Ras activity, when Ras is bound to y activity that removes a phosphate to convert GTP back to GDP and this it is inactive. Activation of Ras involves exchanging GDP for The Ras protein has intrinsic Ras. inactivates activates ATP GTP «< Questic A Moving to another question will save this response. ADP GDP GTPase Clo nuclease

A peptide with the sequence AELQAKSAIAHELQAKAAIAHA is treated with ATP while in the presence of kinase  An alpha helix is formed with the phosphorylated at pH 5  In the direction of the helix axis, what is the length of the helix

Which of the following would result in an increase in the amount of F-2,6-BP? (select all that apply) Group of answer choices high blood glucose activation of fructose bisphosphatase 2 increased phosphofructokinase 2 activity increased glucagon secretion increased phosphorylation of the bifunctional enzyme

S-adenosylmethionine is an activated carrier molecule that transfers which of the following groups? the carboxylic acid group (with one carbon) the phosphate group (with zero carbons) the glucose group (with six carbons) the methyl group (with one carbon) the acetyl group (with two carbons)

Endothelial cells lining blood vessels can produce large amounts of nitric oxide (NO). The NO diffuses out of the endothelial cells and into smooth muscle cells that are in close proximity. In the smooth muscle cells, NO binds to an enzyme, X, to rapidly increase intracellular levels of Y. Y causes rapid relaxation of smooth muscle cells surrounding the blood vessels. The actions of the Y molecule are controlled by enzyme Z which degrades protein Y into a non-functional form, blocking vasoconstriction and retaining high blood flow. Identify molecules X, Y and Z and explain how the drug Viagra targets this pathway.

5) The disease Phenylketonuria (or PKU) occurs when the enzyme that helps to catalyze the conversion of the amino acid phenylalanine into non-harmful tyrosine is mutated and doesn't work as well (or at all). Phenylalanine will still break down into tyrosine by itself, because this is a favorable reaction. Why is the non-functional enzyme a problem? Explain in a few sentences. al.H.colbe91srtihot wolsd sldu non lom i anolterineon mundillups betsmus 8880

I'm a bit confused about this question  will someone help me understand the concept