ATP Synthase contains with in it one of the most conserved residues in a protein we know. Asp 61. This is the amino acid that carries the proton. a. Why would this residue be so highly conserved? What would happen if a mutation occurred that would change Asp to Ala? b. At the end of one spin of ATP synthase when the proton is in a position to leave to the intermembrane space the Asp comes into close contact with another very highly conserved residue Arg 210. Explain how this Arg residue could help the proton attached to Asp to leave. Hint think pKa Answer both parts with good explanation
ATP Synthase contains with in it one of the most conserved residues in a protein we know. Asp 61. This is the amino acid that carries the proton. a. Why would this residue be so highly conserved? What would happen if a mutation occurred that would change Asp to Ala? b. At the end of one spin of ATP synthase when the proton is in a position to leave to the intermembrane space the Asp comes into close contact with another very highly conserved residue Arg 210. Explain how this Arg residue could help the proton attached to Asp to leave. Hint think pKa Answer both parts with good explanation
Human Anatomy & Physiology (11th Edition)
11th Edition
ISBN:9780134580999
Author:Elaine N. Marieb, Katja N. Hoehn
Publisher:Elaine N. Marieb, Katja N. Hoehn
Chapter1: The Human Body: An Orientation
Section: Chapter Questions
Problem 1RQ: The correct sequence of levels forming the structural hierarchy is A. (a) organ, organ system,...
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ATP Synthase contains with in it one of the most conserved residues in a protein we know. Asp
61. This is the amino acid that carries the proton.
a. Why would this residue be so highly conserved? What would happen if a mutation
occurred that would change Asp to Ala?
b. At the end of one spin of ATP synthase when the proton is in a position to leave to the
intermembrane space the Asp comes into close contact with another very highly
conserved residue Arg 210. Explain how this Arg residue could help the proton attached
to Asp to leave. Hint think pKa
Answer both parts with good explanation
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