Which of the following can be identified by anabnormal karyotype?a. Sickle cell diseaseb. Cystic fibrosisc. Monosomy Xd. Tay-Sachs diseasee. Huntington’s chorea
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Which of the following can be identified by an
abnormal karyotype?
a. Sickle cell disease
b. Cystic fibrosis
c. Monosomy X
d. Tay-Sachs disease
e. Huntington’s chorea
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- Two parents, without any family history of cystic fibrosis (CF), have a child with CF. A. What do you predict the genotypes of the parents to be? (CF is a recessive disorder.) B. What is the chance that the next child of these two parents will also have CF?While studying of the family tree with history of hypertrichosis (hyper hirsutism of the ear) this sign was founded only in the men and it was inherited from father to the son. Define the type of hypertrichosis inheritance? Select one: a. Y-linked b. Autosomal-recessive O c. Autosomal-dominant d. Recessive, X-linked e. Dominant, X-linked오오토오 오모 a. What is the mode of inheritance for this rare disease? b. What is the genotype of the following (in cases where the genotype is uncertain, list all possible genotypes.) i. 1.1 ii. 1.2 ii. II.1 iv. I1.4 C. What is the likelihood that II.3 will have a child that is a carrier? d. What is the likelihood that II.2 has three affected children?
- D. Sex-linked In humans, hemophilia is a sex-linked trait. Females can be normal, carriers, or have the disease. Males will either have the disease or not (but they won't ever be carriers). 1. Show the cross of a man who has hemophilia with a normal woman. What is the probability that their children will have the disease? H H = female, normal H h X X = female, carrier h xxn XHY X" Y 2. A woman who is a carrier marries a hemophiliac man. Show the cross. What is the probability that their children will have hemophilia? What sex will a child in the family with hemophilia be? 3. A woman who has hemophilia marries a normal man. How many of their children will have hemophilia, and what is their sex? = female, hemophiliac = male, normal = male, hemophiliac2. STATEMENT: A woman and man both do not have sickle-cell anemia, but both had one parent who had sickle cell. Sickle-cell is an autosomal (somatic) recessive trait. a) What is the genotype for the woman, man and each of their parents? b) This couple unexpectedly is going to have their first child. i. What's the probability that their child will have not have sickle cell like the couple? ii. What's the probability that the child will have sickle cell like one the grandparents?What is the most likely mode of inheritance for the disease depicted in the following pedigree? I II III 1 1 2 1 2 autosomal recessive autosomal dominant 3 3 2 4 4 5 5 6
- 1. What are the symptoms of sickle cell disease (anemia)? 2. What is the genotype of sickle cell disease? Use these sources to find the answers: https://ghr.nlm.nih.gov/condition/sickle-cell-disease#inheritance https://www.cdc.gov/ncbddd/sicklecell/traits.htmlMarfan syndrome is inherited in an autosomaldominant pattern. Which of the following is true?a. Female offspring are more likely to be carriers ofthe disease.b. Male offspring are more likely to inherit thedisease.c. Male and female offspring have the samelikelihood of inheriting the disease.d. Female offspring are more likely to inherit thedisease.What is the frequency of sickle cell disease (anemia)? https://ghr.nlm.nih.gov/condition/sickle-cell-disease#inheritance https://www.cdc.gov/ncbddd/sicklecell/traits.html
- Marfan syndrome is transmitted by a dominant gene.State the probability that a child with an affected parentwill have the disorderReview the process of autosomal dominant inheritance by coloring the following figures. In this instance the father is affected in the mother is unaffected to illustrate the transmission of the disorder from the father to the children color the figures as described.Which of the following does not have an environmental factor thataffects the distribution of the phenotype? a. phenylketonuria c. heightb. skin color d. Marfan syndrome