Which of the following does not have an environmental factor thataffects the distribution of the phenotype? a. phenylketonuria                        c. heightb. skin color                                  d. Marfan syndrome

In this figure, the black circles and squares indicate a genetic disease. A. Based on the pedigree in the figure, does this gene appear to be inherited in a dominant or recessive manner? Explain your prediction. B. Use the letter a to indicate a disease allele and the letter A to indicate a normal allele. Predict the genotypes of the original parents. C. What percentage of the offspring of the original parents would you expect to have the disease? D. Predict the genotype of the partner of the diseased daughter in generation II. Justify your prediction.

a. Each person inherits one copy of the Huntington's Disease gene from each parent. Explain why the negative control sample (from an unaffected individual) only produced one band.   b. Explain why the positive control sample (from an individual affected by Huntington’s disease) produced twobands.

determining coat color is the agouti gene?

A young man went to the doctor because he had small testes and enlarged breasts. Through chromosomal testing, it was determined that this young man had the sex chromosomes XXY. Identify the syndrome with which this young man was MOST likely diagnosed. A. Turner syndrome B. Klinefelter syndrome C. Cri du Chat syndrome D. Down syndrome

The mutations found in the CF gene that result in cystic fibrosis are recessive because.. (Justify your answer)  a) CF is fatal and if the alleles that caused CF were dominant it would not be inheritedb) The CF mutations that occur result in no protein being produced and this is the only possible way for the mutations to be recessivec) Normal or near normal cellular function can occur from the protein produced by the normal allele in a carrierd) CF mutations only result in a protein that has normal function if there is also a normal CF protein in the cell

A researcher is interested in whether a disease gene is linked to an RFLP marker. A cross is made between pure breeding blind cavefish and pure breeding sighted cavefish. The lines are pure breeding. The resulting RFLP markers of the F1 offspring and the F2 (from an F1XF1 cross) offspring are shown.       If the disease gene is 10 m.u. from the RFLP marker, what proportion of the F2 will have the gel pattern shown above AND be blind? Show your work    If the disease gene is 10 m.u. from the RFLP marker, what proportion of the F2 will have the gel pattern above AND NOT be blind? Show your work

One of the first drugs used for targeted cancer therapy is tamoxifen, used to treat estrogen-receptor breast cancer. What general conclusions can you draw about the targeted drug therapy and genotype?

Which of the following would not be consistent with the ideathat a disorder has a genetic component?a. The disorder is more likely to occur among an affectedperson’s relatives than in the general population.b. The disorder can spread to individuals sharing similarenvironments.c. The disorder tends to develop at a characteristic age.d. A correlation is observed between the disorder and amutant gene.

4. In this pedigree of another family with hemophilia A. If the woman Il-2 has a son, what is the chance that he is affected? II B. If the woman Il-2 has a daughter, what is the chance 1 2 3 4 III that she is affected? -1 C. If the woman Il-2 has 2 sons, what is the chance that neither will be affected? D. What are the chances that the child of II-4 and Il-5 will be affected?