When large genomes are sequenced, which of the following is true? Group of answer choices   The genomes are converted from RNA to cDNA using reverse transcriptase, and then the cDNA is sequenced.   The genomes are fragmented, the DNA fragments are sequenced by any number of methods, and the sequences assembled to provide the original complete genome.   Sanger dideoxy sequencing is never used – instead, only nanopore sequencing is used.   The assembled sequences must have all gaps closed if the genome is to be useful for the research community.

Human Anatomy & Physiology (11th Edition)
11th Edition
ISBN:9780134580999
Author:Elaine N. Marieb, Katja N. Hoehn
Publisher:Elaine N. Marieb, Katja N. Hoehn
Chapter1: The Human Body: An Orientation
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When large genomes are sequenced, which of the following is true?
Group of answer choices
 
The genomes are converted from RNA to cDNA using reverse transcriptase, and then the cDNA is sequenced.
 
The genomes are fragmented, the DNA fragments are sequenced by any number of methods, and the sequences assembled to provide the original complete genome.
 
Sanger dideoxy sequencing is never used – instead, only nanopore sequencing is used.
 
The assembled sequences must have all gaps closed if the genome is to be useful for the research community.
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