What would be a likely consequence if step 4 of the citric acid cycle no longer operated far from equilibrium, and instead occurred near equilibrium? the step would need to be coupled to ATP hydrolysis none of these possibilities are likely this step would no longer be a highly regulated step the reaction would no longer occur

What would be a likely consequence if step 4 of the citric acid cycle no longer operated far from equilibrium, and instead occurred near equilibrium? the step would need to be coupled to ATP hydrolysis none of these possibilities are likely this step would no longer be a highly regulated step the reaction would no longer occur

Biochemistry

6th Edition

ISBN:9781305577206

Author:Reginald H. Garrett, Charles M. Grisham

Publisher:Reginald H. Garrett, Charles M. Grisham

Chapter19: The Tricarboxylic Acid Cycle

Section: Chapter Questions

Problem 21P: Complete oxidation of a 16-carbon fatty acid can yield 129 molecules of ATP Study Figure 19.2 and...

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Complete oxidation of a 16-carbon fatty acid can yield 129 molecules of ATP Study Figure 19.2 and determine how many ATP molecules would be generated if a 16-carbon fatly acid were metabolized solely by the TCA cycle, in the form of S acetyl-CoA molecules.
In the first step of the citric acid cycle, an acetyl group from acetyl CoA reacts with oxaloacetate to form (a) pyruvate (b) citrate (c) NADH (d) ATP (e) CO2
If a C18 compound is metabolized and enters the citric acid cycle as nine C2 fragments (acetyl groups), how many molecules of ATP are produced in the common metabolic pathway from C Show your calculations.
In step 7 of the citric acid cycle, fumarase catalyzes the addition of a water molecule to a carbon–carbon double bond (see Panel 13¬–2). Can this be considered an oxidation reaction? Explain your answer.
What steps in the citric acid cycle have each of the following characteristics? a. The reaction generates FADH 2. b. The organic substrate is oxidized. c. The reaction utilizes NAD +. d. The reaction breaks a carbon–carbon bond.
Imagine a triglyceride comprised of (3) saturated C12 fatty acids. Calculate the number of ATP generated from the complete oxidation of one of these 12-carbon fatty acids to CO2 and water in the liver. Assume that each NADH = 2.5 ATP and each FADH2 = ETC generates 1.5 ATP. Any step that yields pyrophosphate as a product should be treated as an input (i.e. net loss) of (2) ATP.
The citric acid cycle is shown. The methyl carbon in acetyl CoA is labeled with C14C14 (shown in red). Identify which of the carbons in each intermediate will be labeled in the first round of the cycle by selecting the indicated carbon(s). Each question has multiple options except citrate. Which carbon in citrate will contain C14? 4 1 3 2 Which carbon(s) in isocitrate will contain C14? 1 2 3 4 5 6 Which carbon(s) in α‑ketoglutarate will contain C14? 1 2 3 4 5 Which carbon(s) in succinyl‑CoA will contain C14? 1 2 3 4 Which carbon(s) in succinate will contain C14? 1 2 3 4 Which carbon(s) in fumarate will contain C14? 1 2 3 4 Which carbon(s) in malate will contain C14? 1 2 3 4 Which carbon(s) in oxaloacetate will contain C14? 1 2 3 4
Explain in complete manner why these 3 became the major pathway that eventually become the entry points for molecules into the Citric Acid Cycle: Glycolysis Oxidation of fatty acid Protein catabolism
The final outputs of the citric acid cycle include all of the following except what molecule? a. CO2 b. ATP c. Oxaloacetate d. FADH2 e. NADP
The molecule FAD is reduced when an ___________ is oxidized to an ____________. In the citric acid cycle we see this as ______________ gets oxidized to ________________.
51. THE ONLY INTERMEDIATE IN THE CITRIC ACID CYCLE WHICH HAVE FIVE CARBON?A. OXALOACETATE B. ALPHA-KETOGLUTARATEC. SUCCINATED. ISOCITRATE 52. THE RATE AT WHICH CITRIC ACID CYCLE OPERATES IS/ARE CONTROLLED BY WHICH OF THE FOLLOWING?A. ATP & NADH LEVELSB. FADH2 & NADH LEVELS C. AMP & ATP LEVELS D. ATP & GTP LEVELS 53. CITRIC ACID CYCLEOR THE KREB'S CYCLE IS WHAT TYPE OF METABOLIC PATHWAY? A. NEITHER LINEAR NOR CYCLIC B. CYCLIC C. LINEAR D. BOTH LINEAR & CYCLIC 54. A NUCLEOTIDE TRIPHOSPHATE WHICH IS INVOLVED IN BOTH PROTEIN AND CARBOHYDRATE METABOLISM? A. UTP B. GTP C. CTPD. ATP 55. A COENZYME WHICH HAVE RIBITOL, THE REDUCED FORM OF RIBOSEAS IT'S SUGAR?A. NAD B. FADH2 C. FAD D. NADH
Some people say that citric acid cycle and the fatty acid oxidation share many similarities. Do you agree with this? Explain with reasons.