What is the final product when using the malonic ester synthesis with the following compound? Write the full transformation diagram (3 steps) with all needed reagents. Br
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- 1. Provide the mechanism of the reaction shown in the picture. 2. Explain why it cannot be done in basic conditions. 3. Why is the enol tautomer favored over the keto tautomer? Ph H3C OH H H3O+/H₂O HO H3C PhWhat is the final product when using the malonic ester synthesis with the following compound? Write the full transformation diagram (3 steps) with all needed reagents. BrPlease complete the following self-Claisen and self-aldol reactions by drawing structures for the missing reactants or products as needed. Thank you!
- Draw a stepwise mechanism for the following reaction. This reaction combines two processes together: the opening of an epoxide ring with a nucleophile and the addition of an electrophile to a carbon–carbon double bond. (Hint: Begin the mechanism by protonating the epoxide ring.)This question has multiple parts. Work all the parts to get the most points. The Stork reaction is a condensation reaction between an enamine donor and an a,ẞ-unsaturated carbonyl acceptor. The overall reaction consists of a three-step sequence of 1. formation of an enamine from a ketone, 2. Michael addition to an a,ẞ-unsaturated carbonyl compound, and 3. hydrolysis of the enamine in dilute acid to regenerate the ketone. Consider the Stork reaction between acetophenone and propenal. 1 Draw the structure of the product of the enamine formed between acetophenone and morpholine. + ChemDoodle [F 10-This question has multiple parts. Work all the parts to get the most points. The Stork reaction is a condensation reaction between an enamine donor and an a,ß-unsaturated carbonyl acceptor. The overall reaction consists of a three-step sequence of 1. formation of an enamine from a ketone, 2. Michael addition to an a,ß-unsaturated carbonyl compound, and 3. hydrolysis of the enamine in dilute acid to regenerate the ketone. Consider the Stork reaction between cyclohexanone and propenal. 1 Draw the structure of the product of the enamine formed between cyclohexanone and pyrrolidine. TAYY { n [F ? ChemDoodle Previous Next
- This question has multiple parts. Work all the parts to get the most points. The Stork reaction is a condensation reaction between an enamine donor and an a,ß-unsaturated carbonyl acceptor. The overall reaction consists of a three-step sequence of 1. formation of an enamine from a ketone, 2. Michael addition to an a,ẞ-unsaturated carbonyl compound, and 3. hydrolysis of the enamine in dilute acid to regenerate the ketone. Consider the Stork reaction between cyclohexanone and propenal. 1 Draw the structure of the product of the enamine formed between cyclohexanone and dimethylamine. Θ کر ? ChemDoodle 106Draw a stepwise mechanism for the following reaction. This reactioncombines two processes: the opening of an epoxide ring with anucleophile and the addition of an electrophile to a carbon–carbondouble bond. (Hint: Begin the mechanism by protonating the epoxidering.)MeH, Ме ОН N. Fill in the necessary reagents to complete the given reaction.
- This reaction is an example of conjugate addition of a nucleophile to an a,ẞ-unsaturated carbonyl. O CH3CH2CH2CH=CHCSCOA H₂O OH CH3CH2CH2CHCH2CSCOA Draw the two resonance structures of the enolate anion intermediate for this reaction. • Draw an R1 group in place of COA. The R group tool is located in the charges and lone pairs drop-down menu. • Draw one structure per sketcher. Add additional sketchers using the drop-down menu in the bottom right corner. • Separate resonance structures using the symbol from the drop-down menu. ->> 90-87 O + ? ChemDoodle >3. Propose a possible synthetic pathway for the following reaction. multiple stepsWhich reagents will give the following synthesis reaction?