WHAT IF? If you measured ADH levels in patients with ADH receptormutations and in patients with aquaporin mutations, what would you expectto find, compared with wild-type subjects?
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WHAT IF? If you measured ADH levels in patients with ADH receptor
mutations and in patients with aquaporin mutations, what would you expect
to find, compared with wild-type subjects?
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- Using molecular cloning, a hybrid receptoer is produced that consists of the extracellular domain of the B-adrenergic receptor (B-AR) and the transmembrane and intracellular domains of the EGF receptor (EGFR). Question: What is the stoichiometric ratio of epinephrine to the hybrid receptor (B-AR-EGFR)? 1:1 O 1:4 O 1:2 2:1 O O Onorypefor he m ch ndohe R le the Problems for practc For each problem state the formula, add the data into the formula, sorve The frst problem has been done for you; this illustrates all the steps you should perform for eacn response pawenA) blirdo 1. Predict the TRC for each of the following individuals. [Write clearyn emuezs blirlo tiertt bas alnensg ari nol 20RT one jerlW () natn Bhe traing noidw 10l noijatoois der oispibni ol 1odmemeA. MALE GENOTYPE FEMALE A of active factor for each TRC= Baseline +( alleles ( active allele actve tactor for eacr TRC= Baseline +(" alleles2 active allele/ AABBCCDE TRC = 80 + (8) (12) TRC = 70 (8) (9) = 80 + 96 176 fingerprint ridges %3D 70 + 72 142 fingerprint ridges %3D = 1. If an A a Bb C cdd male mates with an A a Bb CCDD female, (a) What is the minimum number of ridge-producing genes possible for a child of this couple? (Show your work. Hint: solve gene by gene) (b) what would be the TRC for this child if it is male? (Show your work: give the…Please ASAp. Thanku You discover a new species of frog in extremely dark parts of the Amazon rain forest. You hypothesize that this frog detects light using a mechanism similar to mammals. If you are correct, which of the following types of drugs would interfere with vision in this frog? (can choose more than one choice) a. TRPC blocker b.TRMP5 blocker c. CNG channel blocker d.PDE(phosphodiestrase inhibitor)
- Please provide a good explanation. If the independent variable (IGF-1) is increasing, what would happen to the dependent variable (GHRH)Suppose that you measured binding to the isolated EGF receptor of EGFat various concentrations. Would you expect the binding curve to be hyperbolic? Explain your answer.Recall that when we calculated the fraction of estrogen receptors occupied in the presence of 1 nM estradiol and 1 µM BPA, we found that the fraction of receptors occupied with estradiol was 0.14 and the fraction of receptors occupied with BPA was 0.71. Calculate the concentration of free receptor in terms of the total concentration of receptor, Rtotal 0.29R₁ total 0.86R total 0.85R total 0.15R total Confirm the approximate value for the dissociation Calculate the concentration of free estradiol in terms of the total concentration of receptor, Rtotal Confirm the approximate value for the dissociation constant for the estrogen receptor-estradiol complex.
- Next, compare blood glucose concentrations of wild type mice fed NCD to Cmah mice fed NCD. Do these data support, contradict or say nothing about the hypothesis that the \textit{Cmah} gene does not affect blood glucose? Explain your answer thoroughly.Which ONE of these statements is the most accurate definition of the mode of action of imatinib? Select one: A.It is a specific inhibitor of the BCR‐ABL1 fusion protein and blocks phosphatase activity by competing with adenosine triphosphate (ATP) binding B.It is a specific inhibitor of the BCR‐ABL1 fusion protein and blocks tyrosine kinase activity by competing with adenosine triphosphate (ATP) binding C.It is a specific inhibitor of the BCR‐ABL1 fusion protein and blocks tyrosine kinase activity by interaction with the enzyme site D.It is a specific inhibitor of the BCR‐ABL1 fusion protein and blocks phosphatase activity by interaction with the enzyme siteWHAT IF? Suppose that instead of the PBDG receptor, the researchers hadused a receptor specific for a sweetener that humans crave but mice ignore.How would the results of the experiment have differed?
- Q25. Choose True or False Mammalian cells have a limitless replicative potential. [Choose ] [Choose ] During carcinogenesis, the cancer cell is not eradicated by the body's immune system. False True A breast cancer patient treated with Trastuzumab shows no benefits suggesting that the cancer is caused by HER- [Choose ] 2 receptors. An inactive precursor of an enzyme is referred to as a [Choose ] zymogen. CAR T-Cell Therapy employs the use of T-cells because [Choose] they have memory. Maintenance of blood pressure is not a basic function of the lymphatic system. [Choose ] Fluids squeezed out of blood vessels describes the origin [Choose ] and composition of lymph. A covalent bond is formed between the receptor and the [Choose ] growth factor. >Venurafenib Select one: a. Was developed as a treatment of Gleevec-resistant CML patients b. Inhibits MEK in some melanoma patients c. Melanoma patients with a V600E mutation became resistant to this treatment o d. Inhibits RASFrom the Hill Plot below, the of the first binding event for the receptor-ligand system under study is: Q1 4 nM 10 μΜ -2 nM 2 nM Calculate the Hill Coefficient from the receptor-ligand binding data below: Q2 4 100 2 3 (077) log 10 8 6 4 2 0 -2 -4 -6 -6 -4 -2 0 2 4 log [L] (nM) 6 8 10