what are the effects of PSTMB shown and why is it important to show effects of PSTMB in vitro effects of PSTMB on LDHA? https://www.nature.com/articles/s41598-019-40617-3

What are four benefits of anaerobic glycolysis in tumor cells? https://www.nature.com/articles/s41598-019-40617-3#Tab1

Please explain why the answer is correct and why the other options are incorrect

What are the potential interactions between a specific medication used to treat a cardiovascular condition and a newly discovered compound derived from a rare plant species, and how might these interactions impact the pharmacokinetics and therapeutic efficacy of the medication?

In 1994, the U.S. Public Health Service identified “10 Essential Public Health Services.” For each of the ten, please briefly describe a specific activity that has been used in the response to COVID-19.

The enzymatic activity of PFK1 is generally measured by set- ting up a coupled enzyme assay system whereby aldolase, triose phos- phate isomerase, and glycerol-3-phosphate dehydrogenase are added to the assay mixture. For the latter enzyme, NADH is added and its change in concentration is readily monitored at 340 nm. Write the chain of reactions catalyzed by these enzymes using structural formulas, label substrates and products, and explain why the coupled en- zyme assay system leads to oxidation of NADH. While the chain of reac- tions is similar to those in glycolysis, there is a critical difference because of the dehydrogenase enzyme. Describe how this enzyme causes the chain of reactions to differ from those in glycolysis.

Why is hudroxychloroquine or chloroquine detrimental against  COVID-19?

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Why is de novo biosynthesis of purines markedly elevated in patients with a deficiency in hypoxanthine-guanine phosphoribosyl transferase (HGPRT)? 5-Fluoruracil is converted to methotrexate by a DPD deficiency, leading to increased purine biosynthesis. HGPRT deficiency prevents purine salvage, leading to increased purine biosynthesis to make up for it. HGPRT increases pyrimidine salvage and thereby increases purine biosynthesis as a result. Increased purine biosynthesis is the result of ATP hydrolysis during the production of cyclic AMP.

What is the underlying mechinism of action for the antibiotic Trimethoprin/sulfamethoxazole (SXT)?