What are the approximate fractional concentrations of the following phosphate species at pH values of 0, 2, 4, 6, 8, 10 and 12?
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What are the approximate fractional concentrations of the following phosphate species at pH values of 0, 2, 4, 6, 8, 10 and 12?
-
- H3PO4
- H2PO4-
- HPO42-
- PO43-
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- Acetazolamide is a carbonic anhydrase inhibitor that is used to treat glaucoma. It has two acidic groups and has 2 pKb’s as shown below: What is the concentration of dihydrogen acetazolamide (BH22+) in a 0.5000 M solution of acetazolamide (B)? What is the concentration of hydronium ion (H+) in a 0.5000 M solution of acetazolamide (B)?Acetazolamide is a carbonic anhydrase inhibitor that is used to treat glaucoma. It has two acidic groups and has 2 pKb’s as shown below: What is the concentration of acetazolamide (B), in a 0.5000 M solution of acetazolamide (B)? What is the concentration of hydrogen acetazolamide (BH+) in a 0.5000 M solution of acetazolamide (B)?Shown below is the titration curve for phosphoric acid. At what pH is the solution entirely in the H3PO4 form? 0-0.5 14 12.5 O2.1 NICH
- The glass electrode used in commercial pH meters gives an electrical response proportional to the concentration of hydrogen ion. To convert these responses to a pH reading, the electrode must be calibrated against standard solutions of known H+ concentration. Determine the weight in grams of sodium dihydrogen phosphate (NaH2PO4 · H2O; FW 138) and disodium hydrogen phosphate (Na2HPO4 ; FW 142) needed to prepare 1 L of a standard buffer at pH 7.00 with a total phosphate concentration of 0.100 M . See Problem 24 for the pKa values of phosphoric acid.You have been provided with stock solutions of: stock A: 0.06 M sodium pyrophosphate buffer pH 8.5 stock B: 3 M ethanol stock C: 0.015 M NAD+ stock D: milli Q water Determine the volume you will need of each solution to prepare a buffer of with a final volume of 60 mL containing 10 mM sodium pyrophosphate pH 8.5, 100 mM ethanol, 1 mM NAD+. i.e. volume of stock A = _________mL volume of stock B = _________mL volume of stock C = _________mL volume of stock D = _________mL Show your calculations to arrive at your answers.Normal arterial pH is 7.35 to 7. 45. Both metabolic and respiratory alkalosis have pH more basic compare to the normal arterial pH. The difference is 0.5 units. What is pH value in alkalosis? Niemann-Pick type C disease is a progressive neurological disease; symptoms include unsteady walking with uncoordinated limb movements, slurred speech, a difficulty in swallowing, epilepsy and tremor. This condition is due to the abnormal functioning of a lysosome. State the normal functions performed by this organelle.
- Why Valinomycin is highly selective for K+ relative to Na+?In vitro experiments are conducted at pH = 7.4 to simulate physiological conditions. A phosphate buffer system is often used. H₂PO → H₂PO¹²¯ +H+ pK₁ = 7.2 a. What must be the ratio of the concentrations of HPO to H₂POд ions? b. What mass of NaH2PO4 must be added to 500.0 mL of 0.10 M Na₂HPO4 (aq) in the preparation of the buffered solution?What is the percentage concentration of HNO3 if 25grams of HNO3 is dissolved in enough water to make 1 liter of solution?
- What is the amount of dextrose in mg/kg/min provided by the following TPN for a 60 kg patient? Round to 1 decimal place, do not enter units Dextrose (70%) 320 g Amino acids (8.5%) 92 g Lipids (10%) 44 g sodium chloride 60 mEq sodium acetate 40 mEq Sodium phosphate 15 mmol potassium chloride 80 mEq potassium acetate 30 mEq calcium gluconate 18 mEq magnesium sulfate 8 mEq Multivitamins 10 mL Trace elements 1 mL Total volume: 2640 mL Rate: 110 mL/hrDescribe in detail the steps involved to prepare following solutions;a, 1 Molar anhydrous Ferrous Sulfateb, 1 Normal phosphoric acidc, 0.1 Molal Mohar’ Saltd, 0.2% (v/v) , (v/w), (w/v) and (w/w) solution of acetic acid.PROBLEM 12.27 (a) Use Table 12.5 to calculate the osmotic pressure of the hemodi- alysis solution at 25 °C. (b) If the osmotic pressure of blood at 25 °C is 7.70 atm, what is the direction of solvent movement across the semipermeable mem brane in dialysis? (Blood to dialysis solution or dialysis solution to blood)