What amino acid residue gets phosphorylated on the Receptor Tyrosine Kinase protein?

Q: Cyclic adenosine monophosphate (CAMP) is a molecule that can act as an allosteric activator of…

A: The second messenger cyclic adenosine monophosphate (cAMP, cyclic AMP, or 3',5'-cyclic adenosine…

Q: What are g-coupled protein receptors? Explain the role they play in cell physiology.

A: All cells are protected by a cell membrane or plasma membrane that encloses the cytoplasm and the…

Q: Explain how alternative splicing of mRNA coding for a receptor tyrosine kinase could lead to…

A: The receptor tyrosine kinases are  cell surface receptors that can bind to ligands like polypeptide…

Q: What are the three steps by which receptor tyrosine kinases typically convey an extracellular signal…

A: Answer :  The three steps involved are :- Step1) Ligand Reduction : The receptors present in the…

Q: as uses proteins called ___________________ proteins. These proteins bridge the receptor and Ras…

A: Ras is a group of small GTP-binding proteins, vital for the signal transduction pathway used by the…

Q: Some protein kinases are inactive unless they are phosphorylated on key serine or threonine…

A: There are two type of protein kinase: serine/threonine kinase and tyrosine kinase. The serine/…

Q: Contrast receptors that have intrinsic enzyme activity with thoseassociated with cytoplasmic Janus…

A: Receptors are membrane-bound protein structure, which binds with the ligand and induces cellular…

Q: Which three amino acid residues can be phosphorylated by kinases? What property do these amino acids…

A: Gene expression in organisms is controlled at various levels like at the level of transcription,…

Q: Which isoform of creatinine kinase is found in Muscle?.

A: Isoenzymes are enzyme that have different subunit composition, different amino acid sequence but…

Q: CK1-41 is a non-competitive inhibitor of caspase-1. Explain.

A: Caspases are those proteases which have cysteine protease catalytic triad nucleophile activity and…

Q: Cytokine receptors and tyrosine kinase receptors are similar in all of the following ways EXCEPT…

A: Cytokine receptors are small signaling proteins that help in both immune response and cell…

Q: What is the source of the ATP for the kinase reaction?

A: ATP Kinase : It is an enzyme that catalyses the transfer of phosphate groups from high-energy,…

Q: What are kinases and what is their role in two-componentregulatory systems?

A: An alteration in the surrounding environment causes the bacterial cells to respond by changing their…

Q: Binding of PGI2 to its protein binding receptor leads to

A: Prostacyclin (PGI2) is basically generated in the mammalian vasculature with increased levels in the…

Q: What is the relative inhibition of the kinase if the substrate concentration equals Ks And the…

A: Enzymes are protein molecules that increase the rate of reaction by decreasing the activation…

Q: Compare the three kinases - PKA, PKC, and CaMKinase II in terms of activation. What is the initial…

A: PKA, PKC, and CaMKinase II are three different serine/threonine kinases that play important roles in…

Q: Which of the following are activated either directly or indirectly by a heterotrimeric G protein…

A: Heterotrimeric  G proteins are membrane associated G proteins that form a heterotrimeric complex.It…

Q: What is allosteric regulation? Describe HOW allosteric regulation acts like an “on/off” switch for…

A: The cell signaling is the communication between cells that requires specific signaling molecules…

Q: Protein kinases can be divided into two large groups. Select the option that identifies one of those…

A: Protein kinases are enzymes responsible for adding phosphate groups to proteins. This process is…

Q: Receptor tyrosine kinases such as the epidermal growth factor (EGF) receptor can basically be broken…

A: Receptor tyrosine kinases (RTKs) are a group of membrane-bound receptors that act as signal…

Q: phospholipase C hydrolysis of PIP2 leads to activation of Protein Kinase C.

A: Answer: Instead of adenylyl cyclase another enzyme called phospholipase C is activated by the…

Q: What is protein kinase?

A: Answer- kinase is a type of enzyme that is used to transfer the phosphate group from high energy…

Q: What is the role of lipidated proteins in G-protein-coupled receptors during signal transduction?

A: G-protein coupled receptor refers to the cell surface receptor that recognizes molecules (ligand)…

Q: In which condition is Protein A kinase activated? #1B-arrestin is always active. #2 Lack of kinase…

A: Protein kinase A is a cAMP or cyclic adenosine monophosphate dependent protein kinase as activities…

Q: Which of the following statements about GTP and GTPases is correct? 1. GTPase activating protein…

A: GTPases are an enormous group of hydrolase compounds that binds in the spot to the nucleotide…

Q: What is protein kinase C?

A: Proteins are enzymes that serve as biological catalysts. Catalysts help to speed up chemical…

Q: Members of the integrin family are the major cell surface receptors for many ECM proteins such as…

A: Integrins are a family of αβ heterodimers. Integrins are cellular adhesion receptor molecules that…

Q: Cholera is an acute, diarrheal disease caused by infection of the intestine with the gram-negative,…

A: Proteins are high molecular weight biomolecules made up of amino acid residues linked via peptide…

Q: What is the difference between a protein kinase and a secondmessenger? Can both operate in the same…

A: Signal transduction, also called cell signaling, is the process by which molecular signals are…

Q: Kinesin movement is dependent on GTP hydrolysis.   True   False

A: Kinesin is a motor protein that is essential for the cellular functions like mitosis, transport of…

Q: What do you mean by S-phase cyclindependent kinases?

A: Cyclin-dependent kinases (Cdk) are a family of serine/threonine protein kinases. Cdks play a…

Q: What type of kinase is PKA? (This causes phosphorylation of proteins by transferring the phosphate…

A: Cyclic AMP-dependent protein kinase or protein kinase A (PKA) (EC 2.7.11.11) belongs to the protein…

Q: describe the 3 main players in the GTPase cycle (GTPase, GAP, GEF)

A: Nucleic acid is a molecule that carries the information of the cell and expresses that information…

Q: When a G-coupled receptor is activated, does the By subunit activate any pathways? If yes, describe…

A: G-protein-coupled receptors(GPCRs) are the largest family of cell-surface receptors. The…

Q: protein do cyclin – dependent kinases bind to become active?

A: Cyclin-dependent kinases are protein kinases that play a major role in cell cycle control. They…

Q: What is a caspase? Describe in terms of its molecular function and what cellular function it…

A: The type of cell death known as apoptosis removes cells from the body in a controlled manner without…

Q: What amino acids are often phosphorylated by kinases?

A: Amino acids (AA) are organic molecules that act as the fundamental blocks of proteins. Twenty-one…

Cell Signaling

It allows cells to perform various cellular activities, coordinate, and interact with other cells. All cells of an organism receive signals from their environments and respond accordingly. Even the unicellular eukaryotes receive signals secreted by other cells and respond. In the case of yeast, mating takes place by signaling between the yeast cells. Communication by cell signaling in a multicellular organism has become a vast and important part of various fields of biology.