Human Anatomy & Physiology (11th Edition)
Human Anatomy & Physiology (11th Edition)
11th Edition
ISBN: 9780134580999
Author: Elaine N. Marieb, Katja N. Hoehn
Publisher: PEARSON
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Two pure-breeding strains of mice are crossed to produce F1 mice that
are heterozygous for three linked genes with alleles Aa, Bb, and Dd.
Numerous triply heterozygous F1 mice are testcrossed, and the
genotypes and numbers of the resulting progeny are as follows:
A-
A-
A-
aa
aa
aa
Total
B
B-
bb
bb
B-
B-
bb
dd
dd
dd
10
350
100
40
60
120
320
1000
1.Which gene is in the middle?
2.Specify the genotype of the F1 triple heterozygote as completely as
possible, with the genes in the correct order and the correct alleles on
each chromosome.
3. Which two genes are closest together?
4.What is the map distance between the two closest genes? Assume that
interference is complete between these two genes.
5.If interference is not complete, how will the true map distance differ
from the value you calculated in part (d)? Briefly explain why this is so.
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Transcribed Image Text:Two pure-breeding strains of mice are crossed to produce F1 mice that are heterozygous for three linked genes with alleles Aa, Bb, and Dd. Numerous triply heterozygous F1 mice are testcrossed, and the genotypes and numbers of the resulting progeny are as follows: A- A- A- aa aa aa Total B B- bb bb B- B- bb dd dd dd 10 350 100 40 60 120 320 1000 1.Which gene is in the middle? 2.Specify the genotype of the F1 triple heterozygote as completely as possible, with the genes in the correct order and the correct alleles on each chromosome. 3. Which two genes are closest together? 4.What is the map distance between the two closest genes? Assume that interference is complete between these two genes. 5.If interference is not complete, how will the true map distance differ from the value you calculated in part (d)? Briefly explain why this is so.
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