Two pure-breeding strains of mice are crossed to produce F1 mice that are heterozygous for three linked genes with alleles Aa, Bb, and Dd. Numerous triply heterozygous F1 mice are testcrossed, and the genotypes and numbers of the resulting progeny are as follows: A A- A- A- aa aa aa Total B- D- B- dd bb D- bb dd B- D- B- dd bb D- 10 350 100 40 60 120 320 1000 1.Which gene is in the middle? 2.Specify the genotype of the F1 triple heterozygote as completely as possible, with the genes in the correct order and the correct alleles on each chromosome. 3. Which two genes are closest together? 4.What is the map distance between the two closest genes? Assume that interference is complete between these two genes. 5.If interference is not complete, how will the true map distance differ from the value you calculated in part (d)? Briefly explain why this is so.

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Inheritance and Mendelian Genetics

Inheritance means the passing of traits to offspring from parents. These traits could be passed either through asexual reproduction or sexual reproduction. The offspring receives the genetic material from the parents. Mendelian inheritance is a certain biological inheritance that follows the rules and principles laid down by Gregor Mendel in 1865. The initial hypothesis was considered wrong, but other inheritance theories modified the concept of inheritance and thus genetics.