Two parents who do not have color blindness have a daughter who has only one X chromosome and is color-blind (this genotype is written XO since she is missing an X). Color blindness is inherited in an X-linked recessive manner.

Mary has hemophilia, an X-linked recessive trait. From which of the following individuals could Mary NOT have inherited a hemophilia allele? O Her father O Her father's mother O Her mother's mother O Her father's father O Her mother's father

Adenike and her partner, Debare, are expecting their first child. Adenike is healthy as are her two sisters but her brother has PKU, a recessive disorder of the PAH gene. Genotypically he must be pah-/pah-. Neither of Adenike's parents has PKU but both of her grandmothers did. Debare is a carrier of Sickle Cell trait, which means he has one allele for wildtype hemoglobin (HbA) and one allele for Sickle Cell (HbS), making him HgA/HbS. More importantly, he has two alleles for Marfan Syndrome, a pleiotropic dominant disorder that can affect up to 30 different traits (M+/M+). No one in Debare's family has ever had PKU and no one in Adenike’s family has ever had Sickle Cell or Marfan Syndrome. They consult a genetics counselor over concern of the health of their baby. The genetics counselor collects the medical histories of three generations; their grandparents, their parents, and them. In her calculations, she produces a phenotypic key that indicates M = Marfan, Hb = sickle cell, and pah-…

Please answer both questions in detail. Correct answers are highlighted.

In a parental cross for an autosomal MOI, the ratio (Disease phenotype):(WT phenotype) differ for the scenarios: (i) the father is affected and mother is unaffected; and (ii) the mother is affected and the father is unaffected.  a) true  b) false

In humans, the allele for normal opsins in the cones of the eyes, C, is dominant to the allele for colour- blindness, c. The trait is X-linked. A woman who is not colour-blind has a father who is colour-blind. If this woman has a child with a man who is colour-blind, what is the probability of them having a colour-blind son? Your response must include a Punnett square with correct nomenclature. Express your answer as a frequency between 0-1.

Hemophilia is due to a sex-linked gene. It is recessive and found on the X chromosome. A woman who is a carrier for hemophilia marries a normal man. What will be the possible phenotypes of their children? (use the letter “H”)

Parents Genotype : Bb/bb – Eye Color - (brown eyes dominant , blue eyes recessive) Dd- Dimples ( dominant) Cc/cc- Cleft chin (Dominant) Sarah BbDdcc James bbDdCc   What is the probability that Sarah and James will have a baby girl with blue eyes and dimples

Boe is normal and his wife is not color-blind, she is a carrier. Which of the following children they can't have? all of them carrier daughter normal daughter color-blind son color-blind daughter

Mrs. and Mr. Bond have five children, Janine, Jaliyah, Joliette, Jelani and James Jr. Mr. Bond suffers from fragile X syndrome, an X-linked disease (i.e., on chromosome X) which is also dominant. Mrs. Bond is healthy. Janine, Jaliyah, Joliette and Jelani have fragile X syndrome, while James Jr. is healthy. Is there reason to suspect infidelity in this family?