Tranexamic acid, a drug useful against blood clotting, is prepared commercially from p-methylbenzonitrile. Following is one of the steps in its synthesis, draw the structure of the product of this step.

Q: The storage bottle should be a dark or AMBER-colored reagent bottle

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Q: Show how the p-nitroaniline can be synthesized from benzene:

A: Synthesis of p-nitroaniline from benzene using various processes is described below.

Q: (c) HO.

A: The synthesis of the target molecule starting from the given starting material is proposed below.

Q: Draw the major product of the reaction of 1-butanol and the following reagents. (a) PBr3 (b) SOCI₂,…

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Q: 9.8 x 10-5. 1 10³ 10 6 kg 3 m

A: There is some facts for calculation->-> when two same numbers with different power multiplied…

Q: Show how the benzylamine can be synthesized from benzene:

A: The process is as mentioned below:

Q: Show how acid derivatives are easily interconverted by nucleophilic acyl substitutionfrom more…

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Q: Provide the necessary reagents for the following transformation. Ph `Me Ph `Et

A: 1,3-diketone contain a acidic hydrogen and this hydrogen can be removed in the presence of base to…

Q: Br CH,CO,H +Br, CH,CO,H CH3 `CH,CO,H CH3 A bromolactone

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Q: In the presence of an acid catalyst, acetaldehyde forms a trimer known as paraldehyde. Because it…

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Q: Show how to prepare the following compound by the synthesis of malonic acid

A: Esterification is a process of combining organic acid with an alcohol to form ester and water.…

Q: NaOH

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Q: Identify products A and B from the given 1H NMR data. Treatment of CH2=CHCOCH3 with one equivalent…

A: Addition of a molecule over a double bond is called addition reaction. After addition of HCl, three…

Q: Show how the benzoic acid can be prepared from benzene:

A: Benzoic acid can be prepared from benzene by a 2 step process shown below:

Q: H₂C CH₂ Show how the compound can be synthesized from benzene and alkyl chlorides.

A: Here we have to synthesize the following given compound from the starting material benzene and alkyl…

Q: Brasilenyne is isolated from the digestive gland of the sea hare; it shows significant antifeedant…

A: Alcohols is poor leaving groups to make it good leaving groups treated with SOCl2 to form the alkyl…

Q: Starting with Benzene (or naphthalene or biphenyl) Show a sequence of 3 electrophilic aromatic…

A: Benzene is an aromatic compound. The molecular formula of benzene is C6H6. It contains three double…

Q: How does propane synthesized from propanone? Show its mechanism

A: To solve this problem we will use the Clemmensen reduction.

Q: An oxirane reacts with methylamine to give a product "A". Then, "A" reacts with an oxirane to give…

A: The objective of the question is to identify the product C.

Q: Mustard gas, Cl¬CH2CH2¬S¬CH2CH2¬Cl, was used as a poisonous chemical agentin World War I. Mustard…

A: Sulfur in mustard gas is more nucleophilic than other corresponding oxygen compounds. This is due to…

Q: Suggest a synthesis of the following compound by Claisen or Dieckmann condensations. Show all…

A: 1. Claisen condensation :  Ester in presence of base like NaOEt ( sodium ethoxide) gives followed…

Q: Fluvastatin, a cholesterol-lowering drug, can be prepared by thefollowing three-step reaction…

A: Grubb's catalyst is Ruthenium based catalyst used in olefin metathesis. The structure of Grubb's…

Q: Show how the following ketones might be synthesized from the indicated acids, usingany necessary…

A: This is the reaction given

Q: Propose a synthesis for 3,5-dichloro-2-methoxybenzoic acid starting from phenol.

A: Synthesis for 3,5-dichloro-2-methoxybenzoic acid  from phenol is given as

Q: Draw the structure of the major product for the following two reactions. (PhH = toluene) H L H + +…

A: Aldehyde acts as protecting group of 1,3-diols.  Carbonyl compounds on reaction with phosphorus…

Q: Please give the appropriate reagents to complete the following synthesis.

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Q: The acetoacetic ester synthesis is a carbonyl alkylation reaction. It is used to prepare methyl…

A: Please see attachment below for curved arrow mechanism.Explanation:Step 1:  Step2: The electrons in…

Q: Propose a mechanism for the reaction of benzoic acid with oxalyl chloride. This mechanismbegins like…

A: SOLUTION: Step 1: The best reagents for converting carboxylic acids to acid chlorides are thionyl…

Q: Compound A undergoes an acid-catalyzed hydrolysis. One of the products (B) that is isolated gives…

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Q: 2) Propose the route for the following synthesis.

A: We know that retrosynthesis analysis is one of the most important tools to synthesize any organic…

Q: The acetoacetic ester synthesis is a carbonyl alkylation reaction. It is used to prepare methyl…

A: Answer:  Curved arrow mechanism is shown in the explanation area.Explanation:Step 1:

Q: Show how the benzyl methyl ether can be synthesized from benzene:

A: To show the preparation of benzyl methyl ether from benzene:

Q: Atenolol is a beta blocker medication primarily used to treat high blood pressure and heart-…

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Q: Show how alkylation and acylation of enamines and lithium enolates are usedsynthetically. Give…

A: SOLUTION: Step 1: Enamines are used as intermediates to form carbon-carbon bonds in reactions.…

Q: Prostaglandins are a class of eicosanoids, fatty acid derivatives involved in a variety of important…

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Q: Reaction of diethyl acetamidomalonate with sodium ethoxide to form enolate anion 1; The enolate…

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Reactions at the Alpha Carbon Atom

The position next to the ketone or aldehyde functional group is termed as alpha position and the reaction which occurs at alpha position is called alpha substitution reaction. In an alpha substitution reaction, the alpha proton atom is substituted by an electrophile by the formation of an enol intermediate or enolate ion intermediate. Most of the carbonyl compounds go through an alpha substitution reaction.