They are phenolic compounds. They are monoamine compounds. They act as hormones. They are anionic in nature. They are synthesized in the adrenaline glands. They can be synthesized from tyrosine only. They involve a transmethylation reaction in their synthesis.
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- Outline how an increase in dopamine release can lead to long-term genetic changes using the Dopamine receptor pathway (Starting with DA binding to _____receptor and ending with how it can lead to genetic alterations)Mrs. Jackson, who suffers from seizures, has been stable on a phenytoin dose of 300 mg q.d. (qd or QD) for over a year. However, she has recently been experiencing periods of heartburn. When you ask her more about this, you find there are no red-flag symptoms. She has tried OTC antacids in the past, but did not like them. Instead, she has seen Nexium tablets advertised and wants to know if they would be suitable. Is this an appropriate choice of OTC treatment? Explain in detail and based on scientific reasoning.A patient has a tumour of the chromaffin cells in the adrenal medulla. Whilst awaiting surgery, he is treated with an antagonist which reduces the consequences of adrenal medulla overactivity by binding alpha adrenergic receptors irreversibly. Which one of the following drugs has he been treated with? Answers A - E A Clopidogrel B Lansoprazole C Aspirin Propranolol E Phenoxybenzamine
- Category of biomolecules called catecholamines excludes: 1.Epinephrine 2.Dopamine 3.Thyroxine 4.Nor-adrenalineMedications that inhibit in the brain may cause hyperprolactinemias. O Norepinephrine O Metanephrine O Serotonin O DopamineThe reason a heroin addict feels very ill immediately after going "cold turkey" from heroin is likely a result of upregulation of opiate receptors in the postsynaptic cells. upregulation of endogenous opiates. downregulation of opiate receptors in the postsynatic cells. increased postsynaptic receptor sensitivity. downregulation of opiate reuptake transporters.
- Describe how the process of opioid withdrawal leads to a reduction in the release of dopamine? Explain in a few sentencesAnswer the following: 1.) an indirect agonist that mimics the action of epinephrine and norepinephrine and either stimulate release or block the reuptake of the naturally occuring sympathomimetics 2.) Toxic concentration of alprazolam 3. The only approved indications for use of this drug is for the treatment of attention-deficit hyperactivity disorder (ADHD) 4. An elevated acetylsalicylic acid serum concentration will decrease serum pH and contributes to 5. the metabolism of acute salicylate poisoning follows what order of metabolism kinetic? 6. In TCA poisoning, why is hemodialysis not recommended as a way of treating patient? 7. after an IV administration of this drug an individual feels a pleasurable experience 8, First generation of the tricyclic antidepressant agents 9. An antidote of choice for iron overdose/poisoning 10. Pediatric toxic dose of salicylates 11. Lethal dose of Amphetamine for childrenEpinephrine binds to both β-adrenergic and α-adrenergic receptors. Describe the opposite actions on the effector protein, adenylyl cyclase, elicited by the binding of epinephrine to these two types of receptors. Describe the effect of adding an agonist or antagonist to a β-adrenergic receptor on the activity of adenylyl cyclase.
- People with what condition cannot convert tyrosine into dopamine within the skin? What is the approximate sun exposure needed per week to produce a sufficient amount of 1,25-dihydrocholecalciferol?Draw a table to differentiate Nervous System from the Endocrine System in terms of the following: 1. Molecules released 2. Site of action 3. Types of target cells 4. Onset of action 5. Duration of actionDo amine hormones have intracellular or cell surface receptors? Ex: epinephrine?