Chemistry
Chemistry
10th Edition
ISBN: 9781305957404
Author: Steven S. Zumdahl, Susan A. Zumdahl, Donald J. DeCoste
Publisher: Cengage Learning
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5.1
The total amount excreted into urine as unchanged drug after an oral tablet (A) of 50 mg was
36.4 mg. After an oral capsule dose (B) of 25 mg the U was 20.3 mg. Calculate the relative
bioavailability of the tablet A with respect to capsule B. If the absolute bioavailability of the oral
capsule is determined to be 0.86 calculate the absolute bioavailability of the tablet dosage form.
You are required to list the given data, formula and steps for calculations
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Transcribed Image Text:5.1 The total amount excreted into urine as unchanged drug after an oral tablet (A) of 50 mg was 36.4 mg. After an oral capsule dose (B) of 25 mg the U was 20.3 mg. Calculate the relative bioavailability of the tablet A with respect to capsule B. If the absolute bioavailability of the oral capsule is determined to be 0.86 calculate the absolute bioavailability of the tablet dosage form. You are required to list the given data, formula and steps for calculations
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