Biochemistry
9th Edition
ISBN: 9781319114671
Author: Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.
Publisher: W. H. Freeman
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Question
The most regulated enzyme in glycolysis is
a |
Hexokinase |
|
b |
G3P Dehydrogenase |
|
c |
Pyruvate Kinase |
|
d |
Phosphofructokinase |
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- Which of the following enzymes is the key regulatory step in glycolysis? Phosphofructiokinase-1 is the answer. Explain? A. Phosphoglucose Isomerase B. Phosphofructokinase-1 C. Pyruvate Kinase D. Hexokiase E. Phosphofructokinase-2 ...Why is Phosphoglucose Isomerase wrong?arrow_forwardIdentify the conversion which is not involved in glycolysis. a.Glucose to glucose 6-phosphate by hexokinase b.Triose phosphate to 2-phosphoglycerate by phosphoglyceromutase c.PEP to pyruvic acid by pyruvate kinase d.Sucrose to glucose and fructose by invertasearrow_forwardWhich of the following is TRUE? O Both AMP and ADP are negative regulators of glycogenolysis. ATP shifts the curve of glycogen phosphorylase to the left. O Citrate binds covalently to acetyl CoA carboxylase. Phosphofructokinase-1 is an allosterically regulated enzyme in glycolysis. The carnitine shuttle is positively regulated by Malonyl CoA.arrow_forward
- During which of the following conversions is NADH+H+ formed in the glycolysis cycle? a. Glyceraldehyde 3-phosphate to 1,3-bisphosphoglycerate b. 1,3-bisphosphoglycerate to 3-Phosphoglycerate c. 2-Phosphoglycerate to Phosphoenolpyruvate d. Phosphoenolpyruvate to Pyruvatearrow_forwardDuring Krebs cycle, the conversion of isocitrate to alpha-keto glutarate involves all of the following reactions/mechanisms except Reduction of isocitrate Reduction of NAD+ Decarboxylation of isocitrate Oxidation of isocitratearrow_forwardWhich of the following conditions is most likely to lead to the activation of pyruvate dehydrogenase? High concentrations of acetyl-CoA High concentrations of NADH High concentrations of NAD+ High concentrations of CO2arrow_forward
- In glycolysis, pyruvate kinase produces what high energy product and what low energy product?arrow_forwardWhich of the following enzymes do not catalyze a reaction in the citrate cycle that produces CO2 as a product? Choose one or more: OA. isocitrate dehydrogenase OB. fumarase L C. succinate dehydrogenase O D. succinyl-CoA synthetasearrow_forwardWhich of the following Krebs cycle enzymes generates a molecule of FADH2 from FAD? a-ketoglutarate dehydrogenase pyruvate dehydrogenase isocitrate dehydrogenase malate dehydrogenase succinate dehydrogenasearrow_forward
- What type of regulation would be expected when anaerobic metabolism is occurring in the muscle? Select all that apply. 1. Activation of pyruvate dehydrogenase kinase 2. Increased levels of calcium to activate pyruvate dehydrogenase phosphatase 3. Phosphorylation of pyruvate dehydrogenase 4. Inhibition of pyruvate dehydrogenase complex 5. Increased levels of NADH to activate citrate synthase 6. Increased levels of NADH to inhibit alpha-ketogluterate dehydrogenase complex 7. Increased levels of acetyl CoA to activate pyruvate carboxylase for gluconeogenesisarrow_forwardGluconeogenesis occurs in liver and kidney. Which is of the following enzyme are important for gluconeogenesis are expressed exclusively in these tissues? Select one: a. Glucose-6-phosphatase b. Fructose-1,6-Bisphosphatase c. Phosphoenolpyruvate carboxykinase d. Pyruvate carboxylasearrow_forwardin the mitochondria pyruvate is converted into acetyl CoA so then acetyl CoA make its way to the TCA cycle and produces energy sources for oxidative phosphorylation. Pyruvate oxidation transforms pyruvate, a three-carbon molecule, into acetyl, a two-carbon molecule linked to Coenzyme A, generating NADH and releasing one carbon dioxide molecule in process the citric acid cycle is fundamental because runs on acetyl CoA as its fuel. i need more explanantionarrow_forward
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