The following diagram indicates how the cell cycle progresses in typical human cells: INTERPHASE G₁ MITOTIC (M) PHASE Mitosis Cytokinesis DRUG S (DNA synthesis) G2 Suppose that you are investigating potential drugs that might be used to stop the out of control growth of tumor cells. The following table lists several experimental drugs along with some information about their effect on cells. Predict which stage of the cell cycle might be inhibited by each of the drugs (A through E). COMMENTS Shown to block the

The following diagram indicates how the cell cycle progresses in typical human cells: INTERPHASE G₁ MITOTIC (M) PHASE Mitosis Cytokinesis DRUG S (DNA synthesis) G2 Suppose that you are investigating potential drugs that might be used to stop the out of control growth of tumor cells. The following table lists several experimental drugs along with some information about their effect on cells. Predict which stage of the cell cycle might be inhibited by each of the drugs (A through E). COMMENTS Shown to block the

Human Physiology: From Cells to Systems (MindTap Course List)

9th Edition

ISBN:9781285866932

Author:Lauralee Sherwood

Publisher:Lauralee Sherwood

Chapter1: Introduction To Physiology And Homeostasis

Section: Chapter Questions

Problem 6RE: Cell specializations are usually a modification or elaboration of one of the basic cell functions....

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Which of the following describes the most likely property of cancer cells, other than un- controllable division? A inability of chromosomes to align during the metaphase B с D alteration of the cell cycle sequence inability to undergo apoptosis inability to form spindle fibers
BPA is a chemical compound that has historically been used in themanufacture of plastic products. However, cells often mistake BPAcompounds for hormones that accelerate the cell cycle. Because ofthis, BPA is associated with an increased risk of certain cancers. Question: Why do you think that very small concentrations of BPA mighthave a large effect on the cell?
Which of the following is least likely to result in the formation of a cancerous cell? A Dysfunction results in the permanent activation of a cell division pathway in the absence of the appropriate ligand. B с D Separation of chromatids during mitosis occurs without all centromeres being attached to spindle fibers from both poles. A dysfunction in a cell cycle checkpoint prevents a cell from entering the S phase. A dysfunction causes the inability to produce cancer-suppressing proteins.
Which of the following best describes a way in which a normal growth factor can stimulate cell division? A A growth factor can bind to membrane receptors and initiate a signal transduction path- way that causes the synthesis of division-facilitating enzymes. B с D A growth factor can supply necessary biomolecular building blocks for cell division by diffusing through the cell membane. A growth factor can facilitate the transport of glucose into the cell, thereby providing it with nutrients to support cell division. A growth factor can inhibit specific checkpoints in the cell cycle and allow the cell to skip or bypass certain cell cycle phases.
Artificially induced apoptosis (controlled cellular death) is found to be an effective treat- ment for some forms of cancer. Which of the following describes the most likely mechanism by which apoptosis might be induced? A B с D by causing ribosomes to increase the rate of protein synthesis by triggering the division of mitochondria in the cell to increase ATP production by increasing the expression of membrane-bound glucose protein channels by causing lysosomes to release digestive enzymes into the cytosol
Describe the role of cell division in at least one of the following areas of biology: Stem cell research Cell cloning for organ replacement therapies Cancer (see the DNA LC’s video on tumor growth for a hint: https://dnalc.cshl.edu/resources/3d/31-tumor-growth.html)
Name: Period: Date: Cell Cycle Cell growth and division occurin a regular cycle. This cycle is divided into fourphases: G1, S, G2, and M. The diagram shows this cycle, along with events that occur in each phase. Follow the prompts below. v Color the phase in which most cell growth occurs BLUE v Color the phase in which DNA replication occurs RED. v Color the phase in which preparation for mitosis occurs in YELLOW. v Color the phase in which mitosis and cytokinesis G2 occur in GREEN. P 1. Which three phases make up interphase? GI M 2. Which of the following best describes cancer? Circle the correct answer. uncontrolled cell growth cells stop growing 3. If a dog has 72 chromosomes in a SOMATIC cell, how many chromosomes will its daughter cells have after meiosis_? mitosis_?
If a drug interferes with the formation of microtubules , its effectiveness must be related to disruption of mitotic spindle formation suppression of cyclin production inhibition of DNA synthesis myosin denaturation and inhibition of cleavage formation
Cell growth and division occurin a regular cycle. This cycle is divided into four phases: G1, S, G2, and M. The diagram sh ows this cycle, alongwith events that occur in each phase. Follow the prompts below. v Color the phase in which most cell growth occurs BLUE v Color the phase in which DNA replication occurs RED. v Color the phase in which preparation for mitosis G2 occurs in YELLOW. v Color the phase in which mitosis and cytokinesis occur in GREEN. 4. Which three phases make upinterphase? GI M 5. Which of the following best describes cancer? Circle the correct answer. uncontrolled cell growth cells stop growing 6. If a dog has 72 chromosomes in a SOMATIC cell, how many chromosomes will its daughter cells have after meiosis_? mitosis_? P.
In your own words, explain how cancer cells differ from normal cells in regard to the following: Molecular controls of the cell cycle (include Cdk and Cdk/cyclin complexes, p53 gene/protein, Rb gene/protein in response)
Cell cycle can be controlled by chemical messages and regulate any error by control system?
Which of the following statements best describes the process of phase separation in cells? Proteins can assemble as liquid droplets that are not bounded by a membrane in either the cytoplasm or nucleus A protein can separate into different organelles dependent on the phase of the cell cycle Proteins that are assembled in one phase of the cell cycle and degraded in the next are said to undergo phase separation Signal sequences can target proteins assembled in the cytoplasm into the lumen of the endoplasmic reticulum