The FIGURE 1 below shows the Bohr shift occurs in fetal haemoglobin (P and Q) and for maternal haemoglobin (R and S). 100 90 80 P pH 7.6, Q pH 7.4 70 60 50 R pH 7.6 -S pH 7.4 40 30 20 10 20 40 60 80 100 120 Po,(mm Hg) FIGURE 1 a) Define Bohr shift. State the effect of Bohr shift on the oxygen dissociation curve. b) Compare the oxygen dissociation curve for fetal and maternal haemoglobin. Explain. What happens to the oxygen dissociation curves when the pH is lowered? Explain. Percent 02 saturation of hemoglobin

Cardiopulmonary Anatomy & Physiology
7th Edition
ISBN:9781337794909
Author:Des Jardins, Terry.
Publisher:Des Jardins, Terry.
Chapter15: Hemodynamic Measurements
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The FIGURE 1 below shows the Bohr shift occurs in fetal haemoglobin (P and Q) and for maternal haemoglobin (R and S).
100
90
80
P pH 7.6,
Q pH 7.4
70
60
R pH 7.6
-S pH 7.4
50
40
30
20
10
20
40
60
80
100
120
Po,(mm Hg)
FIGURE 1
a) Define Bohr shift. State the effect of Bohr shift on the oxygen dissociation curve.
b) Compare the oxygen dissociation curve for fetal and maternal haemoglobin. Explain.
c) What happens to the oxygen dissociation curves when the pH is lowered? Explain.
d) Give TWO reasons why an expectant mother is advised to give up the smoking.
e) Sketch the curve for fetal myoglobin at pH 7.6. Label the curve as X.
Percent O2 saturation of hemoglobin
Transcribed Image Text:The FIGURE 1 below shows the Bohr shift occurs in fetal haemoglobin (P and Q) and for maternal haemoglobin (R and S). 100 90 80 P pH 7.6, Q pH 7.4 70 60 R pH 7.6 -S pH 7.4 50 40 30 20 10 20 40 60 80 100 120 Po,(mm Hg) FIGURE 1 a) Define Bohr shift. State the effect of Bohr shift on the oxygen dissociation curve. b) Compare the oxygen dissociation curve for fetal and maternal haemoglobin. Explain. c) What happens to the oxygen dissociation curves when the pH is lowered? Explain. d) Give TWO reasons why an expectant mother is advised to give up the smoking. e) Sketch the curve for fetal myoglobin at pH 7.6. Label the curve as X. Percent O2 saturation of hemoglobin
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