The enzyme that catalyzes the C-Cg bond cleavage reaction that converts serine to glycine removes thesubstituent (R) bonded to the a-carbon in the first step of the reaction. Starting with PLP bound to serine inan imine linkage, propose a mechanism for this reaction. (Hint: The first step involves removal of the protonfrom serine's OH group.)

The chemical structure for PLP, serine, and glycine is shown below.

Answered: The enzyme that catalyzes the C-Cg bond…

Organic Chemistry

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Chapter26: Biomolecules: Amino Acids, Peptides, And Proteins

Section26.SE: Something Extra

Problem 39AP

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