The cells that line the mammalian intestine produce glycoproteins with O-linked oligosaccharides. Some of the glycoproteins remain anchored to the cell surface and some are released into the intestinal space. In a healthy animal, numerous microbial species (the microbiome) live in the intestine. These organisms produce fucosidase, an enzyme that hydrolyzes glycosidic bonds involving fucose. (a) Why is this enzyme useful to the micro organisms? (b) Pathogenic (disease-causing) bacteria typically lack fucosidase. How does this help prevent the growth of pathogens in the intestine, particularly during an illness when the human host stops eating?
Nucleotides
It is an organic molecule made up of three basic components- a nitrogenous base, phosphate,and pentose sugar. The nucleotides are important for metabolic reactions andthe formation of DNA (deoxyribonucleic acid) and RNA (ribonucleic acid).
Nucleic Acids
Nucleic acids are essential biomolecules present in prokaryotic and eukaryotic cells and viruses. They carry the genetic information for the synthesis of proteins and cellular replication. The nucleic acids are of two types: deoxyribonucleic acid (DNA) and ribonucleic acid (RNA). The structure of all proteins and ultimately every biomolecule and cellular component is a product of information encoded in the sequence of nucleic acids. Parts of a DNA molecule containing the information needed to synthesize a protein or an RNA are genes. Nucleic acids can store and transmit genetic information from one generation to the next, fundamental to any life form.
The cells that line the mammalian intestine produce glycoproteins with O-linked oligosaccharides. Some of the glycoproteins remain anchored to the cell surface and some are released into the intestinal space. In a healthy animal, numerous microbial species (the microbiome) live in the intestine. These organisms produce fucosidase, an enzyme that hydrolyzes glycosidic bonds involving fucose. (a) Why is this enzyme useful to the micro organisms? (b) Pathogenic (disease-causing) bacteria typically lack fucosidase. How does this help prevent the growth of pathogens in the intestine, particularly during an illness when the human host stops eating?
Oligosaccharides : It is a saccharide polymer containing a small number of monosaccharides. It can have many functions including cell recognition and cell binding.
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