Glycolysis Pentose phosphate pathway Glucose-6-phosphate Lipopolysaccharide (polysaccharide) Fructose-6-phosphate Ribose-5-phosphate Nucleotides Peptidoglycan Dihydroxyacetonev phosphate amino acids Erythrose-5-phosphate (histidine) Amino acids Lipids (phenylalanine, (glycerol tryptophan, tyrosine) component) 3-phosphoglycerate Amino acids (cysteine, glycine, serine) Phosphoenolpyruvate Amino acids (phenylalanine, tryptophan, tyrosine) Руruvate Pyruvate Amino acids (alanine, leucine, valine) Acetyl-CoA Acetyl-CoA Lipids (fatty acids) Oxaloacetate FIGURE 6.28 The Use of Precursor Amino acids Metabolites in Biosynthesis The size of the x2 a-Ketoglutarate arrows indicates the relative quantity of each precursor metabolite needed to produce a given weight of E. coli cells. (aspartate, asparagine, isoleucine, lysine, methionine, threonine) Amino acids (arginine, glutamate, glutamine, proline) TCА сycle

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If an E. coli cell lost the ability to use the pentose phosphate pathway, which amino acids would it require as growth factors?

Glycolysis
Pentose phosphate
pathway
Glucose-6-phosphate
Lipopolysaccharide
(polysaccharide)
Fructose-6-phosphate
Ribose-5-phosphate
Nucleotides
Peptidoglycan
Dihydroxyacetonev
phosphate
amino acids
Erythrose-5-phosphate
(histidine)
Amino acids
Lipids
(phenylalanine, (glycerol
tryptophan,
tyrosine)
component)
3-phosphoglycerate
Amino acids
(cysteine,
glycine, serine)
Phosphoenolpyruvate
Amino acids
(phenylalanine,
tryptophan, tyrosine)
Руruvate
Pyruvate
Amino acids
(alanine,
leucine, valine)
Acetyl-CoA
Acetyl-CoA
Lipids
(fatty acids)
Oxaloacetate
FIGURE 6.28 The Use of Precursor
Amino acids
Metabolites in Biosynthesis The size of the
x2 a-Ketoglutarate
arrows indicates the relative quantity of each
precursor metabolite needed to produce a given
weight of E. coli cells.
(aspartate, asparagine,
isoleucine, lysine,
methionine, threonine)
Amino acids
(arginine, glutamate,
glutamine, proline)
TCА сycle
Transcribed Image Text:Glycolysis Pentose phosphate pathway Glucose-6-phosphate Lipopolysaccharide (polysaccharide) Fructose-6-phosphate Ribose-5-phosphate Nucleotides Peptidoglycan Dihydroxyacetonev phosphate amino acids Erythrose-5-phosphate (histidine) Amino acids Lipids (phenylalanine, (glycerol tryptophan, tyrosine) component) 3-phosphoglycerate Amino acids (cysteine, glycine, serine) Phosphoenolpyruvate Amino acids (phenylalanine, tryptophan, tyrosine) Руruvate Pyruvate Amino acids (alanine, leucine, valine) Acetyl-CoA Acetyl-CoA Lipids (fatty acids) Oxaloacetate FIGURE 6.28 The Use of Precursor Amino acids Metabolites in Biosynthesis The size of the x2 a-Ketoglutarate arrows indicates the relative quantity of each precursor metabolite needed to produce a given weight of E. coli cells. (aspartate, asparagine, isoleucine, lysine, methionine, threonine) Amino acids (arginine, glutamate, glutamine, proline) TCА сycle
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