The binding of iron regulatory protein (IRP) to the iron response element (IRE) in the 5′ region of the ferritin mRNA results in the a. inhibition of translation of the ferritin mRNA. b. stimulation of translation of the ferritin mRNA. c. degradation of the ferritin mRNA. d. both a and c.
Gene Interactions
When the expression of a single trait is influenced by two or more different non-allelic genes, it is termed as genetic interaction. According to Mendel's law of inheritance, each gene functions in its own way and does not depend on the function of another gene, i.e., a single gene controls each of seven characteristics considered, but the complex contribution of many different genes determine many traits of an organism.
Gene Expression
Gene expression is a process by which the instructions present in deoxyribonucleic acid (DNA) are converted into useful molecules such as proteins, and functional messenger ribonucleic (mRNA) molecules in the case of non-protein-coding genes.
The binding of iron regulatory protein (IRP) to the iron response element (IRE) in the 5′ region of the ferritin mRNA results in the
a. inhibition of translation of the ferritin mRNA.
b. stimulation of translation of the ferritin mRNA.
c. degradation of the ferritin mRNA.
d. both a and c.
The functioning of many different enzymes that are crucial for the survival of an organism require iron. It is required in optimal amounts as too low amount of iron will affect the functioning of the enzymes, while too high amount could be toxic to an organism. Iron is carried in the bloodstream by transferrin, while it is stored in another protein called ferritin. Binding of iron regulatory protein to the iron response elements in the mRNA of both the proteins regulates their synthesis in the cell.
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