Some prion-related diseases, such as familial fatal insomnia, areinherited. How would you expect the mutation has altered the PrPgene in this case? Would it have affected the promoter, the regulatorysequences, or the coding sequence of the PrP gene?

Biology 2e
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ISBN:9781947172517
Author:Matthew Douglas, Jung Choi, Mary Ann Clark
Publisher:Matthew Douglas, Jung Choi, Mary Ann Clark
Chapter16: Gene Expression
Section: Chapter Questions
Problem 18RQ: IS. Alternative splicing has been estimated to occur in more than 95% of multi-exon genes. Which of...
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Some prion-related diseases, such as familial fatal insomnia, are
inherited. How would you expect the mutation has altered the PrP
gene in this case? Would it have affected the promoter, the regulatory
sequences, or the coding sequence of the PrP gene?

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Step 1

 Familial fatal insomnia is a medical condition characterized by insomnia or trouble sleeping. This prion disease is caused due to mutation in the gene that encodes PrPC proteins. This protein helps in the normal functioning of the nervous system and also regulates short term and long term memory. 

 

 

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