Shuffling of amino group to generate glutamate Removal of basic and acidic functional groups Conversion to individual amino acids Glutamate becomes alpha- ketoglutarate Mechanical digestion to go to the small O o O O intestines Conversion of pepsinogen to pepsin by O O HCI Acidic denaturation O O and hydrolysis of proteins Conversion of proteins to simpler polypeptides Enters the Kreb Cycle Active transport takes place O O O O O O O

Shuffling of amino group to generate glutamate Removal of basic and acidic functional groups Conversion to individual amino acids Glutamate becomes alpha- ketoglutarate Mechanical digestion to go to the small O o O O intestines Conversion of pepsinogen to pepsin by O O HCI Acidic denaturation O O and hydrolysis of proteins Conversion of proteins to simpler polypeptides Enters the Kreb Cycle Active transport takes place O O O O O O O

Biochemistry

9th Edition

ISBN:9781319114671

Author:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.

Publisher:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.

Chapter1: Biochemistry: An Evolving Science

Section: Chapter Questions

Problem 1P

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V. Activities Activity 1 Complete the table below by supplying the information required. Brief definition, properties (how the reaction occurs) and reaction that takes place (substance where reaction occur) Lipid Oxidation Browning Protein Denaturation Definition Properties Reaction takes place 4
Enumerate the different enzymes involved in the following lipid metabolic pathways. Show schematically the role of each using relevant reactions that they catalyze. Do not forget to label your substrates and products properly. You may illustrate and/or explain elaborately if necessary. 1. beta-oxidation 2. lipogenesis (towards 1 molecule of triacylglycerol)
Give the Steps, Enzyme/s involved, Electron carriers, ATP Generation, End product and significance of the following metabolic pathway: Lipid Metabolism (explain in 1-3 sentences only) P.S add row if necessary
96. Which one of the following is the correet match of the site of the action on the given substrate, the enzyme acting upon it and the end product ? (1) Duodenum:Triglycerides Tryp sin Fatty acid (2) Small intestine:→protein Pepsin Amino acid (3) Stomach:→Nucleic acid Nuclease nucleotide (4) Ileum:→Dipeptides Dipeptidase Amino acid
b. You conduct some additional experiments to elucidate the starlase metabolic pathway. Your results are shown below. Use this information alongside information from the complementation table above to place the intermediates in the correct order on the pathway. (HINT: use the complementation groups from the table above to help you consolidate information on the tables below. Reference practice question 3 from today's lecture for help). Mutant 1 2 3 4 5 6 Precursor --> [Select] None [Select] Addition to minimal medium starlase + + + + + + --> starlase P + + [Select ] T + O + c. Mutant 2 has a loss-of-function mutation for which enzyme in the starlase synthesis pathway? [Select] E1 E2 E3 E4 Precursor → Intermediate 1 → Intermediate 2 → Intermediate 3 → starlase
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