Increase of ATP concentration Dephcsphorylation of glycogen phosphorylase Increase of glucose-6- phosphate concentration Decrease of ADP concentration Clear All Decreasing glycogen synthesi Increasing glycogen synthesis No effect on glycogen synthesis
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- Different control mechanisms are used to regulate the synthesis of glycogen. Match the action on the left with the effect on the right. Increase in the concentration of inorganic phosphate ion Decrease in the activity of phosphoprotein phosphatase Phosphorylation of glycogen phosphorylase Dephosphorylation of glycogen synthase Ű Clear All Decreasing glycogen synthesis Increasing glycogen synthesis No effect on glycogen synthesisWhich enzyme activity of the glycogen debranching enzyme is operating during the release of glucose units linked to glycogen branchpoints via a1,6 glycosidic linkage? O phosphorylase activity O phosphatase activity O transferase activity O glucosidase activityWhich enzyme activity of the glycogen debranching enzyme is operating during the release of glucose units linked to glycogen branchpoints via a1,6 glycosidic linkage? phosphatase activity phosphorylase activity glucosidase activity transferase activity
- Two of the bypass reactions of gluconeogenesis involve: phosphorylation of the metabolite using phosphate from Pi. ☐ phosphorylation of the metabolite using phosphate from ATP. dephosphorylation of the metabolite without using it to make ATP. phosphorylation of ADP using phosphate from the metabolite.Which of the following drives glycogenesis forward? O Phosphorylated glycogen synthase Dephosphorylated glycogen phosphorylase O Dephosphorylated glycogen synthase O Phosphorylated glycogen phosphorylaseIdentify the enzymes that are required for the synthesis of a glycogen particle starting from glucose 6-phosphate. glycogen synthase kinase UDP-glucose pyrophosphorylase glycogen phosphorylase branching enzyme glycogen synthase
- What is the effect of a defective a(1→ 4) phosphatase in Pompe's disease (GSD II)? O Accumulation of abnormal, unbranched glycogen, leading to heart or liver failure and short fife expectancy O Glycogen accumulation in heart, leading to heart failure, muscle weakness, short life expectancy O Absence of UDP-glucose conversion to glycogen, leading to lack of muscle glycogen, exercise intolerance Glycogen accumulation due to lack of glucose-6-phosphate conversion to glucose, leading to liver enlargement, hypoglycemia, short life expectancy O Lack of complete degradation of glycogen to glucose. leading to mild hypoglycemia, enlarged liver and muscle weakness Submit Request AnswerGlycogen synthase may be regulated by covalent modification and/or allosteric control. Label the diagram with the appropriate terms to describe glycogen synthase regulation. Use the following options: Glucose-6-Phospate; Insulin; Fructose-2,6-Bisphosphate; Phosphorylation, DephosphorylationWhy does the lack of glucose 6-phosphatase activity in the brain and muscle make good physiological sense? Glucose 6-phosphatase allows cells to trap glucose in the cell; however, these tissues primarily rely on noncarbohydrate energy sources. Glucose 6-phosphatase allows cells to generate glucose through gluconeogenesis; however, gluconeogenesis only takes place in the liver. Glucose 6-phosphatase allows cells to release glucose into the blood; however, these tissues should never release glucose. Glucose 6-phosphatase provides glucose 6-phosphate for glycogen synthesis; however, these tissues do not need glycogen.
- Which of the following is true for role of glucose-6-phosphate in the regulation of carbohydrate metabolism? -Glucose-6-phosphate allosterically activates glycogen phosphorylase -Glucose-6-phosphate allosterically inhibits glycogen synthase -Glucose-6-phosphate allosterically inhibits hexokinase kinase -None of the above are correct For a reaction A + B --> C + D, [A] is 0.1M, [B] is 0.1M, [C] is 0.1M, and [D] is 0.1M. which of thefollowing is true? -It is a near-equilibrium reaction -The standard free energy change equals 0.00 -The equilibrium constant equals 1.00 -Mass action ratio equals 1.00What glycolytic intermediate is fructose converted to in the muscle, such that it can be utilized in glycolysis? Glucose 6-phosphate Fructose 6-phosphate Glyceraldehyde 3-phosphate Dihydroxyacetone phosphateWhich enzyme is used in gluconeogenesis that bypasses step 1 of Glycolysis in the production of free glucose from Glucose 6-phosphate? Group of answer choices Hexokinase Glucose 6 phosphatase Glucokinase Glucose 1-phosphatase