Human Anatomy & Physiology (11th Edition)
11th Edition
ISBN: 9780134580999
Author: Elaine N. Marieb, Katja N. Hoehn
Publisher: PEARSON
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Cystic fibrosis is determined by simple dominant-recessive inheritance, where the trait for cystic fibrosis is recessive. Given Rnormal, r is CF gene, complete the following Punnett square
Transcribed Image Text:Rr female
Rr male
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- The pedigree below represents the inheritance of a rare genetic disorder (members joining the pedigree are not carriers). Consider the following pedigree and answer questions (i) to (vii) below. The allele descriptors are B/b. What is the mode of inheritance in this pedigree ? Y-linked inheritance X-linked recessive inheritance X-linked dominant inheritance Autosomal recessive inheritance Autosomal dominant inheritance What is the genotype of individual III-2 ? a) XbXb b) XBXB c) XBXb d) Bb e) bb What is the genotype of individual IV-3 ? a) XbXb b) XBXB c) XBXb d) Bb e) bb Individual IV-4 and an unaffected woman is planning a family. What is the probability that their first child will be phenotypically normal ? a) chance that the first child will be phenotypically normal. b) chance that the first child will be phenotypically normal. c) chance that the first female child will be phenotypically normal; all male children will be phenotypically normal. d) chance that the…arrow_forwardHemophilia is an X-linked recessive gene. A normal woman who is a carrier for hemophilia marries a man with hemophilia. Draw a punnett square of a cross between these two individuals. What are the chances that this couple will have a daughter with hemophilia?arrow_forwardIs the sickle cell allele dominant or recessive? Explain. What is sickle cell trait?arrow_forward
- Complete a new Punnett square below, for a woman who is a carrier for sickle cell, who is married to a man who has sickle cell. What are the possible genotypes that you can identify, what is the ratio of phenotypes that are possible, and what is the chance that any of the offspring are affected by sickle cell anemia?arrow_forwardIf a man with type O blood has a child with a woman who has type AB blood, what are the possible blood types for the child?arrow_forwardO. 2 Hemophilia A is an X-linked trait where blood clotting is affected due to a mutation in a clotting factor protein. Georgio has hemophilia and attends a support group where he meets Gbenga, who does not have the disease, but whose father has hemophilia. Her mother is not affected. A) If they marry, what percentage % of all their children will have hemophilia? % B) Georgio meets another woman, Maria, at the hemophilia support group. Maria also lacks the trait, but her mother has hemophilia while her father is unaffected. # 3 Would a Georgio-Maria mating provide a larger chance of having afflicted children compared to a Georgio-Gbenga mating? C) Show how you came up with your answer to B. Edit View Insert Format Tools Table 12pt ✓ 80 F3 V Paragraph ✓ $ 4 Yes or No 000 000 F4 DO LO % 5 BIUAV T² | F5 ^ MacBook Air 6 2 F6 V & 7 F7 * 8 DII F8 ( 9 DD F9 1 0 S Farrow_forward
- Sickle cell anemia is inherited as an autosomal recessive condition. It also exhibits incomplete dominance in that the heterozygous genotype displays a mild form of the disease known as sickle cell trait while individuals with the homozygous recessive genotype have a severe form of SCA. A man who has severe sickle cell anemia marries a woman who suffers from a mild trait. What is the probabilitu they will have a child with severe SCA?What is the probability they will have a child with mild SCA? What is the probability they will have a normal child? Show ALL work using punnett squares.arrow_forwardIf two people with sickle cell traits (AS genotype) have children, what are the chances that these parents will have three children with the AS genotype. AA genoype if normal, AS is heterozygous, and SS is homozygous for sickle cell disease.arrow_forwardIdentify the type(s) of trait in the pedigree below autosomal recessive autosomal dominant X-linked dominant X-linked recessive Y-inkedarrow_forward
- Draw the following pedigree and identify the mode of inheritance (only identify by shading individuals who express the trait). Please provide the genotype for each individual. Remember if you cannot identify whether an individual is TT or Tt please use the T- annotation: The grandmother expresses the trait and the grandfather does not. The first daughter does not express the trait and marries a man who does not express the trait. The second daughter does not express the trait and marries a man who does not express the trait. The son of the first daughter and her husband expresses the trait. The second son of the first daughter and her husband does not express the trait. The second daughter and her husband have twin daughters that do not express the trait.arrow_forwardIf the mother is blood type AB , the father is Blood type O . Could the daughter who has type O be their child?arrow_forwardCystic Fibrosis is an autosomal recessive disorder. A couple are both carriers of the recessive allele (both heterozygous (Cc)) and have the normal wild-type phenotype. What is the probability of the following occurring; If they have two children, what is the probability of them both being unaffected (CC or Cc) by the disease?arrow_forward
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