Red–green color blindness in humans is due to an X-linked recessive gene. A woman whose father is color blind possesses one eye with normal color vision and one eye with color blindness. a. Propose an explanation for this woman’s vision pattern. Assume that no new mutations have spontaneously arisen. b. Would it be possible for a man to have one eye with normal color vision and one eye with color blindness?

Red–green color blindness in humans is due to an X-linked recessive gene. A woman whose father is color blind possesses one eye with normal color vision and one eye with color blindness. a. Propose an explanation for this woman’s vision pattern. Assume that no new mutations have spontaneously arisen. b. Would it be possible for a man to have one eye with normal color vision and one eye with color blindness?

Human Heredity: Principles and Issues (MindTap Course List)

11th Edition

ISBN:9781305251052

Author:Michael Cummings

Publisher:Michael Cummings

Chapter11: Genome Alterations: Mutation And Epigenetics

Section: Chapter Questions

Problem 16QP: Familial retinoblastoma, a rare autosomal dominant defect, arose in a large family that had no prior...

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In humans, color vision depends on genes encoding three pigments. The R (red pigment) and G (green pigment) genes are close together on the X chromosome, whereas the B (blue pigment) gene is autosomal. A recessive mutation in any one of these genes can cause color blindness. Suppose that a color-blind man married a woman with normal color vision. The four sons from this marriage were color-blind, and the five daughters were normal. Specify the most likely genotypes of both parents and their children, explaining your reasoning. (A pedigree drawing will probably be helpful.) (Problem 50 is by Rosemary Redfield.)
Fragile X is a disorder which causes mental impairment in affected individuals. The trait which is due to a mutation in the FMR1 gene on the X chromosome is inherited in a recessive manner. An unaffected son was born to an affected man and an unaffected woman. The woman’s mother was affected while the father was normal. a. Indicate the gene notation. b. Give the genotype of the son. c. Is it possible for the couple to have an affected daughter? affected son? Derive the genotypic and phenotypic ratios for the offspring. Show and label your solutions properly. d. If the couple has four children, what is the probability that they will have three normal daughters and one normal son?
Colorblindness and hemophilia are both X-linked traits in humans. Explain how a female who has a defective color vision gene on one X chromosome and a defective blood clotting gene causing hemophilia on the other X chromosome can be neither a hemophiliac nor colorblind? Please discuss the effect of Gene dosage compensation in your answer and in your answer describe the molecular process by which this occurs.
Choose correct option and do explain. Considering an X-linked dominant trait, if an affected woman and an unaffected man decide to have children, which of the answer choices is possible for their children? a. All of their sons are expected to show the dominant trait. b. Their daughters are expected be heterozygous for the gene. c. Their daughters are not expected to show the dominant trait. d. Their sons are expected to be heterozygous for the gene. e. All their children, whether male or female, are expected to show the dominant trait.
a. Determine if the pedigree below can be for a trait that is X-linked traits. Write the genotype of each individual next to the symbol. b. Is it possible that this pedigree is for an X-linked recessive trait? c. What can you conclude about the children if both parents are affected with an X-linked recessive trait?
Anhidrotic ectodermal dysplasia is an X-linked recessive disorder in humans characterized by small teeth, no sweat glands, and sparse body hair. This trait is usually seen in men, but women who are heterozygous carriers of the trait often have irregular patches of skin with few or no sweat glands (see the illustration below). a. Explain why women who are heterozygous carriers of a recessive gene for anhidrotic ectodermal dysplasia have irregular patches of skin lacking sweat glands. b. Why does the distribution of the patches of skin lacking sweat glands differ among the females depicted in the illustration, even between the identical twins?
Fragile X syndrome is an X-linked recessive Achondroplasia is an autosomal dominant trait characterized by a shortened stature. An XX individual is a carrier for Fragile X disorder and is unaffected by achondroplasia. An XY individual is not affected by Fragile X disorder and has achondroplasia. a. What is the XX individual’s genotype b. What is the XY individual’s genotype? c. If the two individuals where to have children, what are the possible genotypes and phenotypes of their children? Use a Punnett square. d. What is the probability of them having a child with Fragile X and achondroplasia?
A couple who are both heterozygous for an autosomal recessive mutation that is narrowly expressed and fully penetrant are planning on having three children. What is the probability that one their children will be normal (unaffected) and two children will have the recessive mutant phenotype? Show your work. Please answer this question using the Bayes’ Theorem
Color blindness in humans is an X-linked recessive trait. This means that... O a. Females are more likely to be color blind than males b. The gene associated with color blindness is found on the X chromosome, and an individual must have one (in males) or two (in females) mutant copies of the allele in order to be diagnosed as being color blind
Anhidrotic ectodermal dysplasia is an X-linked recessive disorder in humans characterized by small teeth, no sweat glands, and sparse body hair. This trait is usually seen in men, but women who are heterozygous carriers of the trait often have irregular patches of skin with few or no sweat glands (see the illustration below). Q. Explain why women who are heterozygous carriers of a recessive gene for anhidrotic ectodermal dysplasia have irregular patches of skin lacking sweat glands.
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Familial retinoblastoma, a rare autosomal dominant defect, arose in a large family that had no prior history of the disease. Consider the following pedigree (the darkly colored symbols represent affected individuals): a. Circle the individual(s) in which the mutation most likely occurred. b. Is the person who is the source of the mutation affected by retinoblastoma? Justify your answer. c. Assuming that the mutant allele is fully penetrant, what is the chance that an affected individual will have an affected child?