Biochemistry
Biochemistry
9th Edition
ISBN: 9781319114671
Author: Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.
Publisher: W. H. Freeman
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Recall from the central dogma that DNA codes for mRNA, which then codes for
protein. Also recall that directionality matters!
DNA 3' TAC - CTA -AAT - TGC - TCG-ATT 5'
mRNA 5' ???- ???- ???- ???- ???- ??? 3'
protein
? ?
? ? ?
(A) Indicate whether the DNA sequence provided is the sense strand or the
antisense strand.
?
that
(B) For the DNA sequence given above, write out the mRNA sequence that results.
(C) Now write the amino acid sequence that results from the mRNA sequence
you wrote in part (B). Use the three-letter abbreviations for the amino acids.
(D) What happens if the A that is bolded and underlined in the given DNA sequence
is mutated (changed) to a C? How is the protein affected? This can be answered in a
few words, but be specific!
(E) Now let's pretend for a moment that the protein being affected is ATP-ADP
translocase. What, if anything, would happen to the citric acid cycle? This should be
answered in a few words/one sentence max.
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Transcribed Image Text:Recall from the central dogma that DNA codes for mRNA, which then codes for protein. Also recall that directionality matters! DNA 3' TAC - CTA -AAT - TGC - TCG-ATT 5' mRNA 5' ???- ???- ???- ???- ???- ??? 3' protein ? ? ? ? ? (A) Indicate whether the DNA sequence provided is the sense strand or the antisense strand. ? that (B) For the DNA sequence given above, write out the mRNA sequence that results. (C) Now write the amino acid sequence that results from the mRNA sequence you wrote in part (B). Use the three-letter abbreviations for the amino acids. (D) What happens if the A that is bolded and underlined in the given DNA sequence is mutated (changed) to a C? How is the protein affected? This can be answered in a few words, but be specific! (E) Now let's pretend for a moment that the protein being affected is ATP-ADP translocase. What, if anything, would happen to the citric acid cycle? This should be answered in a few words/one sentence max.
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