Reaction A, an E2 reaction with a strong, small, base: KOH, Br 1-propanol Reaction B, an E2 reaction with a strong, bulky base: KOC(CH3)3 HOC(CH3)3 Br and/or and/or

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Which alkene product would you expect to be the major product under kinetic conditions? Under thermodynamic conditions? The given pictures are the reactions in which we have to determine which alkene product we expect would be the major product under kinetic and thermodynamic conditions.

organic substrate
2-bromo-2-methylbutane
2-bromo-2-methylbutane
2-methyl-2-butanol
Reaction A, an E2 reaction with a strong, small, base:
KOH,
1-propanol
Reaction B, an E2 reaction with a strong, bulky base:
KOC(CH3)3
HOC(CH3)3
reaction
BABC
с
Br
Br
reagent
potassium hydroxide in 1-propanol
potassium 1-butoxide in 2-methyl-2-butanol
phosphoric acid
and/or
and/or
Transcribed Image Text:organic substrate 2-bromo-2-methylbutane 2-bromo-2-methylbutane 2-methyl-2-butanol Reaction A, an E2 reaction with a strong, small, base: KOH, 1-propanol Reaction B, an E2 reaction with a strong, bulky base: KOC(CH3)3 HOC(CH3)3 reaction BABC с Br Br reagent potassium hydroxide in 1-propanol potassium 1-butoxide in 2-methyl-2-butanol phosphoric acid and/or and/or
Reaction C, an acid catalyzed El reaction with a tertiary alcohol:
H3PO4
and/or
OH
For each of these reactions, make a prediction as to which alkene you expect to be the major product, and
which you expect to be the minor product.
The ratio of alkene products for each reaction will be determined using gas chromatography. The alkene
product with the lower boiling point should have the lower retention time. The gas chromatogram will
Transcribed Image Text:Reaction C, an acid catalyzed El reaction with a tertiary alcohol: H3PO4 and/or OH For each of these reactions, make a prediction as to which alkene you expect to be the major product, and which you expect to be the minor product. The ratio of alkene products for each reaction will be determined using gas chromatography. The alkene product with the lower boiling point should have the lower retention time. The gas chromatogram will
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