Reaction 10 of glycolysis involves the generation of pyruvate fromphosphoenolpyruvate (PEP). ATP is also generated in this reaction. Thisreaction is catalysed by the enzyme?a. Pyruvate isomeraseO b. Pyruvate synthaseC.Pyruvate enolaseO d. Pyruvate Kinase

Glycolysis is a metabolic pathway in our body which generates pyruvic acid from glucose . The…

Answered: Reaction 10 of glycolysis involves the…

Biochemistry

9th Edition

ISBN:9781319114671

Author:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.

Publisher:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.

Chapter1: Biochemistry: An Evolving Science

Section: Chapter Questions

Problem 1P

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Which of the following molecules shown are the reduced products produced in the citric acid cycle whose reduction directly helped drive oxidation? Select all that apply. Ensure you are selecting the product forms of the molecule, which here means the reduced form, and are only considering redox reactions! Do not include the pyruvate processing steps -- just the citric acid cycle itself. A. GDP B. NADH C. FAD D. Acetyl-CoA E. NAD+ F. CoA G. FADH2 H. GTP I. QH2 J. Q
In which of the given steps of TCA cycle one C is lost from substrate in the form of CO2 as well as a molecule of NAD+ is reduced? a.Oxalosuccinic acid to a-ketoglutaric acid b.Isocitrate to oxalosuccinic acid c.Malic acid to oxaloacetic acid d.a-ketoglutaric acid to succinyl CoA
1a. If you wanted you could take a glucose molecule and convert it to pyruvate via glycolysis and convert it back to glucose via gluconeogenesis. What is the cost of doing so in ATP equivalents? Show how you determine the cost via reactions (no structures). Explain in bioenergetic terms how the conversion of pyruvate to phosphoenolpyruvate in gluconeogenesis overcomes the large, negative standard free- energy change of the pyruvate kinase reaction in glycolysis. b. C. The consumption of alcohol (ethanol), especially after periods of strenuous activity or after not eating for several hours, results in a deficiency of glucose in the blood, a condition known as hypoglycemia. The first step in the metabolism of ethanol by the liver is oxidation to acetaldehyde, catalyzed by liver alcohol dehydrogenase: CH3CH2OH + NAD+ -> CH3CHO + NADH + H+ Explain how this reaction inhibits the transformation of lactate to pyruvate. Why does this lead to hypoglycemia?
You are treating a cell with Rotenone or MG132 and measuring the molar ratio between NADH/NAD+ (see figure). What can you conclude about Rotenone? * p<0.01 A. Rotenone inhibits glycolysis B. Rotenone inhibits pyruvate oxidation C. Rotenone inhibits the citric acid cycle D. Rotenone inhibits the electron transport chain F. Rotenone inhibits the Golgi apparatus
Increased citric acid levels in the blood will stimulate which of the enzymes listed below? Select one: O a. transketolase O b. pyruvate carboxylase O c. enolase d. acetyl-CoA carboxylase O e. transaldolase No of ATP formed per turn of the citric acid cycle. Select one: O a. 7 Ob. 10 O c. 9 O d. 12 The most abundant product of the reactions of the Krebs cycle is Select one: O a. GTP O b. carbon dioxide c. reduced co-enzymes O d. pyruvate O e. water A regulator of the enzyme glycogen synthase is: Select one: O a. pyruvate b. 2,3 bisphosphoglycerate (2,3 BPG) O c. GTP O d. citric acid O e. glucose-6-phosphate Clear my choice
Glyceraldehyde 3-phosphate dehydrogenase is used to do which of the following steps of glycolysis Select one: a. 1,3 Bisphosphoglycerate is converted to 3-phosphoglycerate b. Phosphoenolpyruvate is converted to pyruvate c. 2-phosphoglycerate is converted to Phosphoenolpyruvate d. Glyceraldehyde-3-phosphate is converted to 1,3 Bisphosphoglycerate e. Fructose-6-phosphate is converted to Fructose-1,6,bisphosphate f. Dihydroxyacetone (Glycerone Phosphate) is converted to Glyceraldehyde-3-phosphate g. Fructose-1,6 Bisphosphate is converted to Dihydroxyacetone and Glyceraldehyde-3-phosphate h. Glucose-6-phosphate is converted to Fructose-6-phosphate i. 3-phosphoglycerate is converted 2-phosphoglycerate j. Glucose is converted to Glucose-6-phosphate
1. Put together the sequence of components (numbers) that form the glycolysis pathway and the linked reaction. Choose the sequence from the following metabolites. Also mention the step in which NADH/FADH; is formed along with the number. > Acetyl ÇoA > Glucose. > Pyruvate. > Fructose – 1, 6-bisphosphate > Glucose – 6- phosphate. > Phosphoenol – pyruvate. > 1,3– Bisphosphoglycerate. > Glyceraldehyde 3-phosphate Fructose – 6– phosphate > Glycerol 2-phosphate /2-phosphoglycerate. Dihydroacetone – phosphate.
Given what you know about the function of the glyoxylate cycle and the regulation of the citric acid cycle, propose control mechanisms that might regulate the glyoxylate cycle.
b and e are wrong, please give the correct answer and explan

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Reaction 10 of glycolysis involves the generation of pyruvate from phosphoenolpyruvate (PEP). ATP is also generated in this reaction. This reaction is catalysed by the enzyme? a. Pyruvate isomerase O b. Pyruvate synthase Pyruvate enolase С. O d. Pyruvate Kinase