Biochemistry
9th Edition
ISBN: 9781319114671
Author: Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.
Publisher: W. H. Freeman
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- During which of the following conversions is NADH+H+ formed in the glycolysis cycle? a. Glyceraldehyde 3-phosphate to 1,3-bisphosphoglycerate b. 1,3-bisphosphoglycerate to 3-Phosphoglycerate c. 2-Phosphoglycerate to Phosphoenolpyruvate d. Phosphoenolpyruvate to Pyruvatearrow_forwardWhich step in glycolysis is an example of substrate-level phosphorylation? OA. Step 1: glucose + ATP →→ glucose 6-phosphate + ADP + Pi B. Step 3: fructose 6-phosphate + ATP C. Step 7: 1,3-bisphosphoglycerate D. Step 10: phosphoenolpyruvate E. Both c and d ->>> fructose 1,6-bisphosphate + ADP + P₁ + ADP + P₁ → 3-phosphoglycerate + ATP -> + ADP + Pi → pyruvate + ATParrow_forwardIn the last step of glycolysis, phosphoenolpyruvate (PEP) is converted to pyruvate and during this reaction ATP is synthesized. Based on the fact that ATP is synthesized, which of the following enzymes would most likely catalyze this reaction? a. enolase b. pyruvate kinase c. aldolase d. pyruvate isomerase e. pyruvate dehydrogenasearrow_forward
- Which intermediates of glycolysis are used to generate ATP by substrate-level phosphorylation? a. Fructose-1,6-bisphosphate b. Glyceraldehyde-3-phosphate c. 1,3-Bisphosphoglycerate d. 2-Phosphoglycerate e. Phosphoenolpyruvatearrow_forwardPyruvate dehydrogenase complex is the key enzyme that regulates the TCA cycle. De-phosphorylation of this enzyme by phospho-protein phosphatase makes it active. Which of the following compounds is expected to activate phospho-protein phosphatase? Acetyl COA a. O b. NADH Ca²+ O C. O d. ATParrow_forwardAre the following up or down regulation of phosphorylation? (Note: It assumes that the enzymes were involved in glycoysis) a. Phosphofructokinase-2 b. Pyruvate Kinase c. Phosphofructokinase-1 d. Pyruvate Dehydrogenase Kinasearrow_forward
- Steps in oxidative phosphorylation involves all of the following except 11. a. The phosphorylation energy is supplied by ATP metabolism b. Electron transfer chain moves electron from NADH and FADH2 to O2 c. Phosphorylation of ADP to ATP catalyzed by ATP synthase d. Electron do not flow to oxygen unless ATP is needed 12. List factors that can activate glucokinase for glucose metabolism in the liver 13. What are the functions of macromolecules with examples? Write the general balanced equation that shows the catabolism of glucose (GLYCOSLYSIS) to ATPS, carbon dioxide, and water. Include in the equation the formation of ATP from ADP and phosphate and oxygen utilization. 14. 15. What is post-translational processing of proteins and list 3 things that can happen to the proteins synthesized at this stage:arrow_forwardGlycolysis is often split up into three phases: 1. Energy Investment 2. Sugar Splitting and 3. Energy Payoff. After splitting the 6-carbon sugar, Fructose 1,6-biphosphate, 4 ATP are generated by substrate-level phosphorylation. What is substrate-level phosphorylation? A. ATP generated by chemiosmosis B. ATP generated by the direct transfer of a phosphate from an organic molecule to ADP C. ATP generated by the fermentation of alcohol D. Transfer of phosphates between glucose molecules E. All of the abovearrow_forwardWhen completely metabolized, a hexose molecule yields the energy of 36 ATP molecules. Which step of this chemical process yields the most ATP? A. Activation of glucose B. C. D. Phosphorylation of glyceraldehyde 3-phophate Oxidative decarboxylation of pyruvate Metabolism of the two C₂ fragments in common metabolic pathwayarrow_forward
- The first roadblock to overcome in the synthesis of glucose from pyruvate is which of the following reactions? a. Fructose 6-P to Fructose 1,6-bis-P b. Pyruvate to Oxaloacetate c. Pyruvate to Phosphoenolpyruvate d. Phosphoenolpyruvate to Pyruvatearrow_forwardBeside each compound listed, indicate what stage or stages of cellular respiration it is associated with by placing an 'X' in each applicable box. Compound Glycolysis Pyruvate Oxidation Kreb's Cycle ETC/Chemiosmosis a. ATP b. Acetyl-CoA c. Citric Acid d. Coenzyme A e. Glucose f. Pyruvate g. FADH2 h. ATP synthase i. CO2 j. H2O k. O2arrow_forwardIn the first stage of glycolysis, the hydroxyl group on C6 of glucose is phosphorylated to form glucose-6-phosphate (G6P). In this reaction, which of the following statements is true? a. O b. d. e. Glucose kinase is used to catalyze the reaction. Hexokinase is used to catalyze the reaction. A molecule of NADH is synthesized. One ATP is synthesized. Fructose kinase is used to catalyze the reaction.arrow_forward
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