Question 3. An abnormally high levels intracellular tangles are observed to occur in the brains of patients suffering from several fatal neurodegenerative diseases like Alzheimer's disease. These tangles are composed of protein that has an unusually high level of which post-translational modification?

Q: Describe the advantages and disadvantages of the following mechanisms of regulation: Transcriptional…

A: Mechanisms of regulation are very important in regulating the transcription and translation…

Q: What is self-splicing intron? Cite two reasons that suggest cukaryotic spliceosomes originated from…

A: RNA (ribonucleic acid) is the complementary strand of DNA (deoxyribonucleic acid) which is…

Q: Under which conditions does the trp repressor block transcription of the trp operon? when the…

A: The trp operon responds to a repressor protein that binds to two molecules of tryptophan. When the…

Q: What triggers the release of acetylcholine from a synaptic terminal?

A: Note:- Sorry, please note that as per our company's honor code, we are allowed to author only the…

Q: What anticodon sequences of tRNAs are coded for by the mRNA codons below? (Enter each sequence in 5'…

A: An mRNA molecule's complementary sequence forms a binding with the three nucleotides that make up…

Q: The mouse REST gene is under the control of a promoter region which contains alternative promoters.…

A: Ribosomes perform an important function in protein biosynthesis in the cytoplasm. The mRNAs that are…

Q: what are the steps of translation in order based on when they occur? It would be nice if some…

A: Translation is the process by which a protein is synthesized from the information contained in a…

Q: Compare and contrast cotranslational import of polypeptides with posttranslational import of…

A: Import of polypeptides across the membrane bilayer refers to the translocation process. The…

Q: Describe the process of protein synthesis and associated post translational modifications.

A: Post-translational modification (PTM) refers to the covalent and generally enzymatic modification of…

Q: What are the functional consequences of this deletion for lilP mRNA transcription and translation?…

A: Introduction :- A deletion mutation is a type of genetic mutation that involves the loss of one or…

Q: Taking start and stop codon into consideration, if we have an mRNA sequence with 30 nucleotides, how…

A: Peptides are peptide bonds that connect short chains of amino acids. Dipeptides, tripeptides, and…

Q: Question 1 :Provide the anticodon sequence that would build this protein.  Amino acid sequence: MET…

A: Note: Since you have posted multiple questions so we will be solving the first one for you. As per…

Q: Riboswitches... permit transcription elongation only when bound to a small-molecule ligand. are…

A: Riboswitches are the mRNA segments that act as regulatory elements. They are involved in the control…

Q: Explain the posttranslational control ?

A: Introduction Proteins are macromolecules synthesised in a cell’s cytoplasm and are made up of a long…

Q: What are the FOUR ways that protein function is regulated (function turned ON/OFF).  Explain each.

A: Cells have proteins called receptors these receptors bind to signaling molecules and initiate a…

Q: What do you mean by post translational folding?

A: Protein folding takes place in the endoplasmic reticulum and proteins folding an important process…

Q: Translation in prokaryotes: Does the initiation of translation in prokaryotes rely on initiation…

A: The initiation factor does not bind to the Shine-Dalgarno sequence, instead, they are associated…

Q: definition for this question A,B,C, or D ?

A: DNA( deoxyribonucleic acid) is the double-stranded molecule that is the genetic material in most…

Q: What will be the anticodons that will arrive in the translation of MRNA below? MRNA 5 -…

A: The translation is a process of conversion of RNA codon sequences into their respective amino acid…

Q: The following RNA sequence represents a small messenger which can be translated in a prokaryotic…

A: The first step in translating an RNA sequence into a protein is to divide the sequence into codons,…

Q: The terminal inverted repeats of a DNA transposon or a retrotransposon bind an enzyme of what…

A: Transposons are mobile elements present in the genome of an organism. There are responsible for the…

Q: A Class Il aminoacyl-tRNA synthetase installs the formyl-methionine on tRNAMet in bacteria. A…

A: As per the central dogma of molecular biology, genetic information is stored in the DNA. The genetic…

Q: Transcriptional termination generally will include the transcription of an inverted repeat in that…

A: Transcription is the process by which the information in DNA is transcribed onto the mRNA molecule…

Q: Why is posttranslational modification necessary for a protein to be functional?

A: Post-translational Modifications:             The covalent and enzymatic modification of proteins…

Q: QUESTION 37 Which of the following types of mutations is LEAST likely to alter the encoded protein?…

A: Mutation is defined as a sudden change or alteration in sequence of DNA or variation in the…

Q: Removal of the signal peptide and C peptide from pre-proinsulin to ultimately form insulin.…

A: The eukaryotic gene regulation involves different steps, both the transcription and translation…

Q: in the endoplasmic reticulum and Golgi-complex, the determination of proper folding depends on what…

A: One of the most important post-translational modifications of proteins, protein glycosylation has a…

Q: Explain the term posttranslational modifications?

A: Translation refer to the process in which synthesis of protein occurs from an mRNA molecule.

Q: Which is NOT a modification made to pre-mRNA? addition of a 5' cap removal of introns addition of a…

A: The mRNA is produced by the process of transcription. It takes place in the nucleus. The RNA…

Q: The hydropathy plot of a particular hyaluronan synthase is plotted by Heldermon et al and is shown…

A: The hydropathy plot helps the researchers give the understanding of the degree of hydrophobicity or…

Q: Why do frameshift mutations tend to have a more severe consequence than a missense mutation?

A: Mutation is change in a DNA sequence. Mutations can result from: DNA copying mistakes made during…

Q: 1.11 Which post-translational modification prepares proteins for degradation? O Ubiquitinylation O…

A: Post translation modification also called PTM's. These are the few modifications which takes place…

Q: how many amino acids and omega bonds? How many amino acids appear to have undergone a…

A: Amino acids are amphoteric, colorless, and crystalline solids. They are soluble in water and…

Q: Translation work is an essential step for protein synthesis. In order for the protein to be…

A: The expression of genes includes two major process: transcription and translation. In transcription,…

Q: There is a specific enzyme that adds the 5' Cap to mRNA. If an inhibitor of this enzyme were added…

A: Cap in RNA is a molecule of 7 methyl guanosine at 5' end.

Q: In my biochemistry course, we are completing a project where we take the human insulin degrading…

A: Insulin-degrading enzyme (IDE) is zinc-metalloendopeptidase that hydrolyzes insulin and other…

Q: 11.71 Provide the three-letter amino acid sequence expected from each of the following mRNA…

A: mRNA:Messenger ribonucleic acid (mRNA) is a single stranded RNA molecule that is read by a ribosome…

Q: The binding of a codon on mRNA and an anticodon on tRNA has a free energy of -9 kT. What is the…

A: Free energy, also known as Gibb's free energy, is the energy that may be used to do work. Almost…

Q: Translational control is usually aimed at preventing the initiation of translation. With regard to…

A: The process of translating the sequence of mRNA into an amino acid sequence is called translation.…

Q: In the case of the insulin receptor (IR), the RNA-binding protein RBP described in lecture in muscle…

A: RNA binding proteins bids to mRNA based on structure or sequence and form ribonucleoprotein…

Q: The free energy of binding of codon on mRNA and anticodon on tRNA is -9 kT. What is the probability…

A: In thermodynamics, free energy is the function of internal energy, entropy, and enthalpy. The…

Q: True or false: A fully assembled 70S ribosome is recruited to the mRNA just 5 ́ of the translation…

A: The translation begins with the attachment of messenger ribonucleic acid (mRNA) with the ribosome.…

Genomics

Genes are responsible for transmitting the characters located on the chromosomes from one individual to another across the generations. Genetics is the study of different genes that are involved in different functions. Genetics is a branch of biology that studies genes, genetic diversity, and heredity in living organisms. The genetic system consists of genetic notations, which is a system of signs and symbols. Genotype refers to the organism's genetic composition, and phenotype refers to the observable property of the organism.