QUESTION 13 The phenomenon by which an allele containing a deletion in a tumor suppressor gene causes a good copy of the gene carried on the other allele to undergo deletion is an example of OA. Penetrance. OB. Chromatid dysjunction OC. Loss of heterozygosity OD. Allelic exclusion O E. Chromosomal translocation

QUESTION 8 A researcher is trying to determine the relationship between the A gene and 3 other genes (B, C and D). She performs three test crosses to determine if the genes are unlinked, incompletely linked or completely linked. Next to each cross is the ratio for the progeny of the cross. In the 3rd column please indicate whether the gene pair being tested is unlinked, incompletely linked or completely linked. Ratio (Alleles indicate phenotype of progeny) Type of Linkage (incompletely linked, completely linked or unlinked) Crosses AaBb x aabb 1 AB: 1 Ab: 1 aB: 1 ab AaCc x aacc 6 AC: 6 ac: 1 Ac: 1 aC AaDd x aacc 1 AD: 1 ad

Question 17 Individuals with Beckwith-Wiedemann syndrome (Bws) develop sporadic tumors due to a mutation in an imprintable gene, p57, on chrornosome 11. Normally, p57 regulates the cell cycle. The imprint on p57 is such that only the maternal allele is expressed. A heterozygous normal couple has two children with BWS and one normal child. How is it possible that both parents have the mutant p57 allele to pass along, but these parents do not themselves show the cancerous phenotype? A) Each must have received the mutant p57 allele from their respective fathers. B) Each must have received the mutant p57 allele from their respective mothers. C) The mother must have received the mutant p57 allele from her mother, while the father must have received the mutant p57 allele from his father. D) The mother must have received the mutant p57 allele from her father, while the father must have received the mutant p57 allele from his mother. E) Actually, there's something inconsistent here. Such…

QUESTION 2 A loss of function of Apaf1, the human equivalent of ced-4 in C. elegans, is most likely to result in which of the following? activation of a developmental pathway found in C. elegans but not in humans a form of cancer in which normal apoptosis fails excess activation of the human version of the ced-3 protease O extensive tissue damage due to excess apoptosis

My question is two fold. What are some diseases that cause and/or are caused by apoptosis? Also if apoptosis is the most common form of programmed cell death in animals, what other forms of programmed cell death are there? Thank you.

Question 14 The scientist (scientists) who used enzyme-digesting proteins to show that protein was not the genetic information transferred by bacteria is/are: Question 15 What is the role of mRNA? Question 16 The site on homologous chromosomes where crossing over occurs are called ___ Centromeres Chiasmata Kinetochores Spindle fibers

Question 5 What stage of mitosis is shown in the picture? Incorrect 0.00 points out of 2.00 P Flag question Select one: O a. Prophase b. Interphase x c. Metaphase d. Anaphase e. Telophase

Question 3 Anna (who produces eggs) and Syed (who produces sperm), have a child with Down's syndrome that results from trisomy of chromosome 21. Using a microsatellite sequence on chromosome 21, you run a gel. The gel imaged is attached; darker bands indicate signals of twice the intensity. If a nondisjunction event occurred in Anna during meiosis I, which lane (A, B, C, D) best fits the genotype of their child? Explain your choice, clearly identifying why that lane is correct and why the other lanes are incorrect. Assume no recombination.

QUESTION 9 For the following questions, please fill in the blank with the correct number of chromosomes (e.g. 4). Please do not spell out the number (e.g. four) or include any kind of punctuation (e.g. 4.). In an organism where the diploid number of chromosomes is 2N=8, how many chromosomes would you expect to find in cells that are in G2 of the cell cycle? How many DNA molecules would you expect to find in cells that are in G2 of the cell cycle? How many chromosomes would you expect to find in cells that are in metaphase II? How many DNA molecules would you expect to find in cells that are in metaphase II? How many chromosomes would you expect to find in cells that are in anaphase of mitosis? How many DNA molecules would you expect to find in cells that are in anaphase of mitosis?

QUESTION 49 Which of the following is not true/accurate with respect to p53?   a. is a tumor-suppressor   b. is a transcription factor that promotes transcription of inhibitors of the cell cycle   c. is an oncogene   d. is named for its molecular mass (in kiloDaltons)