QUESTION 1 The Wnt signaling pathway component, Dsh, effects the action of B catenin by: O A. inhibiting the function of axin in the destruction complex O B. blocking GSK-3B from joining the destruction complex OC. stimulating ubiquitination of B catenin O D. causing its release into the cytosol from the plasma membrane complex O E. causing an increase in phophorylation of B catenin

Please refer to the model, the answer may be brief.. thank you so much for answering both... i appreciate it1. Explain the mechanism of action of the adenyl cyclic system using a schematic diagram. 2. Cite a metabolic pathway where active protein kinase is needed and explain its mechanism of action

Same question but two different sections

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235) mGluRs are metabotropic receptors that are activated by the binding of the neurotransmitter glutamate. Based on this information, which of the following statements about mGluRs is correct? a. mGluRs open for Cl- ions to flow through in response to activation by glutamate. b. Activation of mGluRs does not result in graded potentials. C. mGluRs activate signaling pathways that act through a second messenger cascade. d. Signal transduction pathways close mGluRs to elicit depolarizations. e. mGluRs are embedded in the membrane of the presynaptic cell.

Lithium ion, which is used to treat bipolar disorder, interferes with the phosphoinositide signaling pathway by inhibiting enzymes such as inositol monophosphatase and inositol polyphosphate 1-phosphatase. Predict the eff ect of Li+ on the supply of cellular inositol, a precursor of phosphatidylinositol and PIP2.

Hello, I copy and paste the article to save image space. Can you please summarize what this paper is about and elaborate the result? The discussion should explain what this article is about. Please summarize the paper and its conclusion as if your explaing step by step to the class.

46. Of the following signaling processes which one is NOT involved in cellular movement or cytoskeletal changes? (3) $ 50000 Ca Binding site catenin (2) CAP Daam1 ROCK Ras GTP Raf Dsh RhoA) SOS MEK (ERK)

Phosphorylase kinase integrates signals from thecyclic-AMP-dependent and Ca2+-dependent signalingpathways that control glycogen breakdown in liver andmuscle cells (Figure Q15–4). Phosphorylase kinase is com-posed of four subunits. One is the protein kinase that cata-lyzes the addition of phosphate to glycogen phosphorylaseto activate it for glycogen breakdown. The other three sub-units are regulatory proteins that control the activity of thecatalytic subunit. Two contain sites for phosphorylation byPKA, which is activated by cyclic AMP. The remaining sub-unit is calmodulin, which binds Ca2+ when the cytosolicCa2+ concentration rises. The regulatory subunits controlthe equilibrium between the active and inactive confor-mations of the catalytic subunit, with each phosphate andCa2+ nudging the equilibrium toward the active confor-mation. How does this arrangement allow phosphorylasekinase to serve its role as an integrator protein for the mul-tiple pathways that stimulate glycogen…