Question 1 For import into the nucleus, proteins require: Ran-GTP active transport Pex5 an NES Question 2 The nuclear envelope contains nuclear pore complexes (NPCs) that allow small molecules to pass but excludes macromolecules larger than 40 kDa True False

Do question 6

QUESTION 31 Which molecule is displaced when a vesicle and its target membrane fuse? OA. Water OB. Phospholipids OC. SNARES OD. DNA O E. Cholesterol QUESTION 32 Which of the following is a possible explanation as to why a transcription factor that you expressed in the cytoplasm using a plasmid stayed in the cytoplasm and did not move into the nucleus? OA. The transcription factor is lacking a nuclear localization signal. OB. The protein lacks a proteasome-targeting sequence. OC. The transcription factor is lacking a signal sequence to direct it to the ER. OD. The transcription factor is lacking a KDEL retention signal. QUESTION 33 A newly formed COPII-coated vesicle has all of the following except OA. Sar 1 OB. Clathrin OC.Sec 13/31 OD. Sec 23/24 OE. V-SNARE

Question 12