Q1. An HIV crime in Washington In 2004, a 32-year old man in the state of Washington was accused of causing "great bodily harm" and convicted of 17 counts of first-degree assault with sexual motivation, leading to 178 years and 1 month in prison. The man learned of his HIV positive status in 1992, yet engaged in more than 1,000 acts of unprotected sex with 17 female partners between 1999 and 2004. Five of these 17 females tested HIV-positive between May 2003 and March 2004. He never informed his partners of HIV and denied having the disease when asked. As part of the court case, scientists were commissioned to carry out a phylogenetic analysis of virus strains circulating in the blood of the man and the 5 women that tested HIV- positive (indicated in color and denoted WA01-WA06). As comparison, the scientists analyzed virus samples obtained from other people living in the same region (indicated in black and denoted as outgroups). The phylogeny, as presented in court, and used as primary evidence, is shown above; note that every individual carried a wide variety of HIV strains (indicated by the tips of the tree). a. In the phylogenetic tree, circle one monophyletic group. b. On the basis of the tree, do all strains collected from the Washington test cases (WA01-WA06) form a monophyletic group? Explain your answer. On the basis of the tree, determine which of the six Washington test cases (WA01-WA06) is the 32-year old man. Explain your answer, and be specific. C.
Q1. An HIV crime in Washington In 2004, a 32-year old man in the state of Washington was accused of causing "great bodily harm" and convicted of 17 counts of first-degree assault with sexual motivation, leading to 178 years and 1 month in prison. The man learned of his HIV positive status in 1992, yet engaged in more than 1,000 acts of unprotected sex with 17 female partners between 1999 and 2004. Five of these 17 females tested HIV-positive between May 2003 and March 2004. He never informed his partners of HIV and denied having the disease when asked. As part of the court case, scientists were commissioned to carry out a phylogenetic analysis of virus strains circulating in the blood of the man and the 5 women that tested HIV- positive (indicated in color and denoted WA01-WA06). As comparison, the scientists analyzed virus samples obtained from other people living in the same region (indicated in black and denoted as outgroups). The phylogeny, as presented in court, and used as primary evidence, is shown above; note that every individual carried a wide variety of HIV strains (indicated by the tips of the tree). a. In the phylogenetic tree, circle one monophyletic group. b. On the basis of the tree, do all strains collected from the Washington test cases (WA01-WA06) form a monophyletic group? Explain your answer. On the basis of the tree, determine which of the six Washington test cases (WA01-WA06) is the 32-year old man. Explain your answer, and be specific. C.
Chapter10: Infection Control
Section: Chapter Questions
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Transcribed Image Text:Question 1- An HIV crime in Washington
WA04
0.78/
1.00/0.68
0.95/5
1.00/5
C.
0.94/0.57
1.00/0.81
0.66/5
0.77
WA01
10.64.
1.000
80/
0.94-
WA06
1.00/0.98
L
0.79
0.89-
0.82/0.55
0.96- 1.000.95
0.83/
4.00
0.85/
1.00/0.98
0.98/0.73
1.00/0.99
1.00/1.00
WA03
00/0.95
0.05
1.000 55
WA05
/960
1.00/0.94
1.00/0.9
1.00/0.90
0/0.94
0.93
0.524
1.00/0.83
-680840/960
1.00/0.78
1.000.69
1.00.0.99
0.821
1,00/1.00
0.93
0.76/
0.97/0.79
00/0.79
1.00/1.00
660/00'L
1.00/1.00
1.00/1.00
0.71/1
070-
1.00/0.99
1,00/1.00
1.00/1.00
1,00/1.00
1.00/1.00
1.00/0.99
1.00/1.00
WA02
1.00/0.99
1.00/1.00
1.00/1.00
WA04
1.00/0.99
1.00/1.00
Outgroups
Q1. An HIV crime in Washington
In 2004, a 32-year old man in the state of Washington was accused of causing "great bodily harm" and convicted of 17
counts of first-degree assault with sexual motivation, leading to 178 years and 1 month in prison. The man learned of his
HIV positive status in 1992, yet engaged in more than 1,000 acts of unprotected sex with 17 female partners between
1999 and 2004. Five of these 17 females tested HIV-positive between May 2003 and March 2004. He never informed his
partners of HIV and denied having the disease when asked. As part of the court case, scientists were commissioned to
carry out a phylogenetic analysis of virus strains circulating in the blood of the man and the 5 women that tested HIV-
positive (indicated in color and denoted WA01-WA06). As comparison, the scientists analyzed virus samples obtained
from other people living in the same region (indicated in black and denoted as outgroups). The phylogeny, as presented
in court, and used as primary evidence, is shown above; note that every individual carried a wide variety of HIV strains
(indicated by the tips of the tree).
a. In the phylogenetic tree, circle one monophyletic group.
b.
On the basis of the tree, do all strains collected from the Washington test cases (WA01-WA06) form a
monophyletic group? Explain your answer.
On the basis of the tree, determine which of the six Washington test cases (WA01-WA06) is the 32-year old
man. Explain your answer, and be specific.
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