MATLAB: An Introduction with Applications
MATLAB: An Introduction with Applications
6th Edition
ISBN: 9781119256830
Author: Amos Gilat
Publisher: John Wiley & Sons Inc
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Q. 3 A researcher calculated the negative predictive value of a test for
carriers of X-linked ornithine transcarbamylase deficiency (OTCD - a
disorder of the urea cycle). A test known as the "allopurinol test" is often
used as a screening device of potential carriers whose relatives are OTCD
patients. Sensitivity and specificity of the allopurinol test is estimated the as
0.927 and 0.997 respectively Also the prevalence is estimated in the
population of individuals with OTCD as (1/32000). Use this information and
Bayes theorem to calculate the predictive value negative of the allopurinol
screening test.
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Transcribed Image Text:Q. 3 A researcher calculated the negative predictive value of a test for carriers of X-linked ornithine transcarbamylase deficiency (OTCD - a disorder of the urea cycle). A test known as the "allopurinol test" is often used as a screening device of potential carriers whose relatives are OTCD patients. Sensitivity and specificity of the allopurinol test is estimated the as 0.927 and 0.997 respectively Also the prevalence is estimated in the population of individuals with OTCD as (1/32000). Use this information and Bayes theorem to calculate the predictive value negative of the allopurinol screening test.
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