Biochemistry
9th Edition
ISBN: 9781319114671
Author: Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.
Publisher: W. H. Freeman
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- Sickle cell anemia is an example of a genetic disease caused by a point mutation. To answer this question look at the information in chapter 3 of the OpenStax book. If you use another resource that is fine but you will need to share the link. a. Describe the specific change in the nucleotide sequence sequence from normal to mutated hemoglobin. b. Describe the specific change in the amino acid sequence from normal to mutated hemoglobin. c. Explain the structural effect that this point mutation has on the hemoglobin protein. d. Explain how this mutation affects the function of the hemoglobin protein.arrow_forwardUse the diagram to answer the following three questions. 5' TTAGGGITAGGGTTAG 3' ||||| 3' AATCCC 5' -Telomerase ČAAUCCCAAUC RNA of telomerase- 3' 5' Write the next six bases that would be added by telomerase using the format 5'NNNNNN3' What does the "RT" stand for in the protein known as TERT (two words)? In order to add more than six bases what must the telomerase do first?arrow_forwardIn gluconeogenesis, only the carbon skeletons of amino acids, not fatty acids, are utilised. So how does fatty acid oxidation in the liver produce brain fuel? Describe the substances and routes involved.arrow_forward
- Discuss the following: “During the evolution of life on earth, RNA lost its glorious position as the first self- replicating catalyst. its role now is as a mere messenger in the information flow from DNA to protein.”arrow_forwardAs determined by comparisons of ancient and recently evolved proteins, cysteine, tyrosine, and phenylalanine appear to be late-arriving amino acids. In addition, they are considered to have been absent in the abiotic Earth. All three of these amino acids have only two codons each, while many others, earlier in origin, have more. Is this mere coincidence, or might there be some underlying explanation?arrow_forward3)Which of the following statements are true? Choose all that apply a)There are multiple codons possible for nearly all amino acids b)Each stop codon also codes for an amino acid c)Each tRNA will base pair with only one codon d)The start codon also codes for an amino acid e)Each codon in mRNA codes for exactly one amino acid f)Each codon in tRNA codes for exactly one amino acid g)Each anticodon in tRNA pairs with exactly one codon h)Each tRNA carries exactly one type of amino acidarrow_forward
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