Prior to entry, the _________ glycoprotein of the HIV virus recognizes the ______ receptor on the surface of the macrophage. a. CCR5; gp120 b. CXCR4; CCR5 c. CD4; CCR5 d. gp120; CD4

You are studying SARS-COV2. You identify a viral protein that results in the decrease of MHC class I, a cell surface receptor, on the cell surface. You are trying to determine the mechanism for how the virus is decreasing cell surface MHC I. You decide to do an experiment to determine whether the receptor is making it all of the way through the secretory pathway. You take two samples of cells. 1. Uninfected 2. Infected with SARS-CoV2 You treat them with EndoH and analyze MHC I on a western blot and get the following results: 1. Uninfected cells - 50% of protein is endo H sensitive and 50% is Endo H resistant 2. SARS-COV2 infected cells - 100% of protein is Endo H sensitive How would you best interpret these results? Is MHC I going all the way through the secretory pathway in infected cells? A. No, MHC I is not going all the way through the secretory pathway. 100% of the protein is EndoH sensitive in infected cells, this means that the virus is somehow inhibiting the protein from making…

Consider the events that occur in HIV infection. I. HIV undergoes molecular self assembly.II. The protein gp120 binds to CD4.III. The HIV genome is incorporated into the host cell genome.IV. Reverse transcriptase is activated.V. The lipid envelope of HIV fuses with the T cell membrane. What is the correct sequence of the numbered events? I > III > V > IV > II IV > II > I > V > III II > V > IV > III > I III > I > II > IV > V

18. Antiviral proteins synthesized in response to the binding of interferon may target a. intracellular uncoating b. nucleic acid synthesis c. viral assembly C. d. viral ribosomes e. all the above except d 19. When a macrophage encounters S. aureus, which of the following will most likely not occur? a. The macrophage will indirectly induce the synthesis of an antibody b. The macrophage will activate T cells C. The macrophage will produce cytokines d. The macrophage will exhibit its phagocytic and antigen presenting traits e. a & b 20. Plasma cells are actually activated by a. an antigen b. a T cell c. a B cell d. a memory cell PRRS e. 21. Development of resistance to a particular antimicrobial is limited if the drug a. binds to several sites on the target molecule b. targets several different molecules c. affects only one molecule d. affects the plasma membrane e. a and b

Which of the following characteristics is true of large Pre-B cells? Select one: a. They do not express CD19 at the cell surface. b. Rearrangement of light-chain genes commences. c. Nonproductive rearrangement of both heavy-chain loci has already occurred. d. Allelic exclusion of the immunoglobulin light-chain loci has already occurred. u is assembled with VpreB25. e.

Which organelle do phagocytes use to digest engulfed particles? a. lysosome b. nucleus c. endoplasmic reticulum d. mitochondria

FceRI binds     A. IgA   B. IgG   C. IgE   D. Innocuous substances   Aspirin reduces inflammation by acting on:     A. Histamine   B. Chymotryptase   C. Leukotrienes   D. Prostaglandins

Why are most unimmunized children protected against diseases such as measles?Choose one: A.  They lack the host cells for viral replication. B.  They are protected by herd immunity. C.  They have developed immunity toward the measles virus. D.  They still have circulating maternal antibodies.

Area MST receives input mainly from (magnocellular / parvocellular / koniocellular) LGN cells. A. Magnocellular B. Parvocellular C. Koniocellular

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