Human Anatomy & Physiology (11th Edition)
11th Edition
ISBN: 9780134580999
Author: Elaine N. Marieb, Katja N. Hoehn
Publisher: PEARSON
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Predict the potential effect of the Lyon hypothesis on the retina
of a human female heterozygous for the X-linked red-green color
blindness trait.
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- Red–green color blindness is caused by an X-linked recessive genetic defect. Hence females rarely exhibit the red–green colorblind phenotype but may be carriers of the defective gene. When a narrow beam of red or green light is projected onto some areas of the retina of such a female carrier, she can readily diff erentiate the two colors, but on other areas she has diffi culty in doing so. Explain.arrow_forwardUsing the link provided. Mate two flies. a male is a wild type and a female has yellow body and purple eyes. Use: https://www.sciencecourseware.org/FlyLabJS/ Which mutant alleles are dominant? Which mutant alleles are recessive? Which mutant alleles are sex-linked? Which mutant alleles are autosomal? Can you tell at this point if the two genes are linked? Show the results of the dihybrid analysis. Are genes segregating independently? What is the evidence for or against this? Show the crosses you will use to obtain the mapping data. For the mapping crosses, Write out the crossing scheme and make a table of the results (ignore sex in this table, combine the male and female progeny). Identify the parental classes and the recombinant classes. For a 3-point cross, identify the double cross overs. Show your calculations for the recombination frequencies between the three genes (for the 3-point cross) or the two genes (for the two-point crosses). Draw a map of…arrow_forwardPredict the probability (using a Punnett square) of producing an offspring affected by a single gene X-linked mutation given the genotype of the parents. Compare these crosses in two cases: where the mutant allele is “A” vs where the mutant allele is “a” (XAXA x XaY) (XAXa x XAY) (XAXa x XaY) (XaXa x XAY) (XaXa x XaY). Include gender in the phenotype.arrow_forward
- What do you think that means about the frequency of X-Linked Traits in people who arebiologically XY?arrow_forwardXX individuals can be sex-reversed males if one of their X chromosomes contains a translocated portion of the Y chromosome that includes the SRY gene. In light of what you now know about X-chromosome inactivation, it seems that this karyotype might have more complex consequences. In fact, although most such males are completely sex-reversed, X-chromosome inactivation can cause some of these XX males to have varying degrees of residual female characteristics. a. X-chromosome inactivation in normal XX embryos occurs earlier in development than SRY production in normal XY embryos. When present on a translocation X chromosome, SRY is subject to inactivation. Formulate a hypothesis to explain why many XX individuals with a translocation X chromosome that includes the SRY gene are not completely sex-reversed (male). b. Based on your answer to part (a), why do you think some individuals with this karyotype are completely sex-reversed?arrow_forwardPlease answer fast:-arrow_forward
- Due to dosage compensation by X inactivation, females can exhibit a mosaic pattern of sweat glands on only some portions of their body if they carry a particular loss of function allele. Could any of the following genotypes result in males with such a mosaic pattern of sweat glands? Explain. A. X^AY B. X^AX^AY C. X^AX^aY D. Not possiblearrow_forwardExplain Maternal effect mutants affecting AP axis patterningarrow_forwardCan the Lyon hypothesis be tested in a human female who is homozygousfor one allele of the X-linked G6PD gene? Why, or why not?arrow_forward
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