Chemistry
Chemistry
10th Edition
ISBN: 9781305957404
Author: Steven S. Zumdahl, Susan A. Zumdahl, Donald J. DeCoste
Publisher: Cengage Learning
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Question

Predict the outcome of the following reaction:

**Chemical Reaction Prediction** **Problem Statement:** Predict the outcome of the following reaction: **Reaction:** A molecular diagram shows a terminal alkyne (a hydrocarbon chain with a triple bond at the end) reacting with the amide ion (NH₂⁻). The reaction arrow prompts the prediction of the reaction's product. **Explanation:** In this reaction, the terminal alkyne is likely undergoing deprotonation by the strong base, the amide ion. Terminal alkynes have a relatively acidic hydrogen atom that can be removed by strong bases. The expected product would be the formation of an acetylide ion, where the alkyne hydrogen is replaced by the negative charge. This type of reaction can be used in organic synthesis to perform subsequent nucleophilic substitution reactions, using the acetylide ion as a nucleophile.
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Transcribed Image Text:**Chemical Reaction Prediction** **Problem Statement:** Predict the outcome of the following reaction: **Reaction:** A molecular diagram shows a terminal alkyne (a hydrocarbon chain with a triple bond at the end) reacting with the amide ion (NH₂⁻). The reaction arrow prompts the prediction of the reaction's product. **Explanation:** In this reaction, the terminal alkyne is likely undergoing deprotonation by the strong base, the amide ion. Terminal alkynes have a relatively acidic hydrogen atom that can be removed by strong bases. The expected product would be the formation of an acetylide ion, where the alkyne hydrogen is replaced by the negative charge. This type of reaction can be used in organic synthesis to perform subsequent nucleophilic substitution reactions, using the acetylide ion as a nucleophile.
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