Please write/describe at least four criteria that make a target druggable and describe with example the importance of the druggable target that you selected for study

Briefly explain this statement "Preformulation studies help to find the drug performance and the development of a dosage form"-explain this with different drug properties and example? Please answer at your own easy words.

What are the advantages of inhalation drug delivery systems over other routes of drug administration ? Please briefly explain at your own words.

Discuss why the increase of time intervals decreases the reaction time for analgesic drug.

Indicate whether each statement is true or false, and justify your answer.Phase III clinical trials are a minor part of the drug development process in the US.

Protease inhibitors are primarily metabolized by the P450 system, and the metabolism of other drugs can be altered in patients taking them. Which of the following drugs has the greatest potential for drug-drug interactions? Ritonavir Saquinavir Stavudine Zalcitabine

Outline the general steps from initial drug discovery to IND filing. Add as much detail as you need and feel free to use flow charts, graphics, visuals, as long as is made by you alone and not directly copied-pasted from another source. If an IND is cleared to proceed by the US-FDA, what is the single most important goal of a first-in-human (FIH) clinical trial?

A quantal dose response data was collected for Drug A to determine ED50. The total number of subjects tested was 100. The equation of the linear portion of the quantal dose-response curve was determined to be y = 0.2316x - 14.337. Calculate the ED50 value for Drug A. Group of answer choices 278 529 420 350

Apart from simple diffusion, suggest TWO ways how do drugs pass through the cell membrane and the properties of the drugs that is suitable for that way.

The plasma of half-life of aspirin is t1/2 = 20 minutes; ibuprofen t1/2 = 2 hours. Both agents are dosed q 4 to 6 hours. Compared to ibuprofen, APAP's dosing can be much longer than it's plasma half-life because it is: 1. more toxic, so cannot be taken as often 2. more selective for COX1 than is ibuprofen 3. an irreversible inhibitor