Please double check the information is done correctly. And, using the information and data, answer the question at the bottom of the second page which asks: “Did your results from the coin tosses support your prediction from the Punnett Square? Specify the data you used.” Write the answer in detail

Biology (MindTap Course List)
11th Edition
ISBN:9781337392938
Author:Eldra Solomon, Charles Martin, Diana W. Martin, Linda R. Berg
Publisher:Eldra Solomon, Charles Martin, Diana W. Martin, Linda R. Berg
Chapter16: Human Genetics And The Human Genome
Section16.3: Genetic Diseases Caused By Single-gene Mutations
Problem 7LO: State whether each of the following genetic defects is inherited as an autosomal recessive,...
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Please double check the information is done correctly. And, using the information and data, answer the question at the bottom of the second page which asks: “Did your results from the coin tosses support your prediction from the Punnett Square? Specify the data you used.” Write the answer in detail
Autosomal Recessive Disorder: Cystic Fibrosis
2. Cystic fibrosis is lethal autosomal recessive disorder in humans. It is the most common fatal
disorder in the United States. Its hallmark is bacterial infections of the lungs and intestine. A
woman who is a carrier of cystic fibrosis (Cc) has children with a man who is also a carrier
(Cc). What are the chances that a particular child will have cystic fibrosis? What are the
chances that a particular child will be a carrier?
a. Phenotypes of the parents:
Mother:
b. Genotypes of the parents:
C.
Gamete genotypes:
d. Punnett Square:
(egg)
Mother:
Сс
Egg: Cc
CF
с
CCC
c/ Cc
(sperm)
с
Cc
сс
Father:
CF
Father: CC
Sperm : CC
e. List all possible genotypes of offspring of these parents: CC, Cc, and cc
1. Which of these genotypes are heterozygous? Cc
2. Which of these genotypes are homozygous? CC and cc
60
f. List all the possible phenotypes of offspring of these parents:
carrier of cystic fibrosis, affected i.e. cystic fibrosis and
nonaffected
g. Calculate the probability of each genotype and phenotype as listed. Fill in table on the
following page.
Transcribed Image Text:Autosomal Recessive Disorder: Cystic Fibrosis 2. Cystic fibrosis is lethal autosomal recessive disorder in humans. It is the most common fatal disorder in the United States. Its hallmark is bacterial infections of the lungs and intestine. A woman who is a carrier of cystic fibrosis (Cc) has children with a man who is also a carrier (Cc). What are the chances that a particular child will have cystic fibrosis? What are the chances that a particular child will be a carrier? a. Phenotypes of the parents: Mother: b. Genotypes of the parents: C. Gamete genotypes: d. Punnett Square: (egg) Mother: Сс Egg: Cc CF с CCC c/ Cc (sperm) с Cc сс Father: CF Father: CC Sperm : CC e. List all possible genotypes of offspring of these parents: CC, Cc, and cc 1. Which of these genotypes are heterozygous? Cc 2. Which of these genotypes are homozygous? CC and cc 60 f. List all the possible phenotypes of offspring of these parents: carrier of cystic fibrosis, affected i.e. cystic fibrosis and nonaffected g. Calculate the probability of each genotype and phenotype as listed. Fill in table on the following page.
Table 3: Expected Probabilities for Cystic Fibrosis
Genotype
probability as a
percent
Genotype Genotype
CC
Cc
CC
CC
probability as a
fraction
114
214
114
Cc
сс
25%
50%.
25%.
Phenotype
Normal
CF
Table 4. Data for Cystic Fibrosis
Genotype Total #
(Total #
genotype genotype
after 24
/24) X
100
tosses
in %
20.8% 25% Normal
54.2% 50%
25% 25%
5
13
6
h. What are the chances a child will have cystic fibrosis?
Report data as a percentage: 25% as a fraction: 4
Phenotype
probability as a
fraction
2/4
i. What are the chances a child will be a carrier of cystic fibrosis?
Report data as a percentage:
50%.
as a fraction:
We are going to test the ratio of offspring given the parental genotypes above for Cystic Fibrosis
by using a coin toss. Obtain the appropriate coins for the mother and father. Follow the previous
coin toss procedure.
314
1/4
CF
Probability Phenotype Total #
from
phenotype
after 24
Punnett
Square in
tosses
%
61
Phenotype
probability as
a percent
75%.
18
25%.
(total #
phenotype
/ 24) x
100
in %
75%.
Probability
from
Punnett
Square in
%
75%
6
25%.
25%
Did your results from the coin tosses support your prediction from the Punnett Square? Specify
the data you used.
Transcribed Image Text:Table 3: Expected Probabilities for Cystic Fibrosis Genotype probability as a percent Genotype Genotype CC Cc CC CC probability as a fraction 114 214 114 Cc сс 25% 50%. 25%. Phenotype Normal CF Table 4. Data for Cystic Fibrosis Genotype Total # (Total # genotype genotype after 24 /24) X 100 tosses in % 20.8% 25% Normal 54.2% 50% 25% 25% 5 13 6 h. What are the chances a child will have cystic fibrosis? Report data as a percentage: 25% as a fraction: 4 Phenotype probability as a fraction 2/4 i. What are the chances a child will be a carrier of cystic fibrosis? Report data as a percentage: 50%. as a fraction: We are going to test the ratio of offspring given the parental genotypes above for Cystic Fibrosis by using a coin toss. Obtain the appropriate coins for the mother and father. Follow the previous coin toss procedure. 314 1/4 CF Probability Phenotype Total # from phenotype after 24 Punnett Square in tosses % 61 Phenotype probability as a percent 75%. 18 25%. (total # phenotype / 24) x 100 in % 75%. Probability from Punnett Square in % 75% 6 25%. 25% Did your results from the coin tosses support your prediction from the Punnett Square? Specify the data you used.
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