phosphorylation/dephosphorylation Diagram the cascade that regulates glycogen metabolism. Please use key enzyme names and arrows to show how glycogen phosphorylase and glycogen synthase are inversely activated/deactivated.
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- In the following diagram of glycolysis. Identify the steps that are amphibolic, taking place in both glycolysis and gluconeogenesis. Also, identify the regulated steps and what compounds act as regulators.Describe the impact of phosphorylation of glycogen phosphorylase on its heterotropic regulation. (Don’t need the structural details; focus on the qualitative effects on allostery; be brief and to the point)Briefly discuss the process of glycogen catabolism in atep by step
- a- During intense exercise the transformation glucose to lactate causes very less ATP production compared to aerobic glycolysis. Explain, does anaerobic glycolysis lead to waste of energy in muscle? b-Glycogen phosphorylase enzyme catalyzes the removal of glucose from glycogen. Describe, glycogen metabolism regulation through glycogen phosphorylase.Protein Phosphatase 1: What overall effect does PP1 have on the storage or breakdown of glycogen? (1 point) How does PPI regulate the activity of its targets? (1 point) Which enzymes are its targets? (2 points) What activates it [hormone (pathway activator) and enzyme (immediate activator)]? (2 points) Hormone: Enzyme:Glycogen synthase may be regulated by covalent modification and/or allosteric control. Label the diagram with the appropriate terms to describe glycogen synthase regulation. Use the following options: Glucose-6-Phospate; Insulin; Fructose-2,6-Bisphosphate; Phosphorylation, Dephosphorylation
- I'm confused about glycolysis and gluconeogenesis. Question: What is the function of glyceraldehyde 3-phosphate dehydrogenase? Is it because of -> The incorporation of a phosphate from ATP and reduction of glyceraldehyde 3-phosphate or ->The incorporation of phosphate from inorganic phosphate and reduction of glyceraldehyde 3-phosphate. or -> The incorporation of phosphate from inorganic phosphate and oxidation of glyceraldehyde 3-phosphateWhat is meant by reciprocal regulation ? Name one compound that reciprocally regulates glycolysis and gluconeogenesis pathways . Which enzymes are regulated by this compound? What reactions are catalyzed by these enzymes (structures not required) ?Please select appropriate word in each bracket Glycogen provides short term energy storage primarily in liver and muscle. Defects in the enzymes that are required for either glycogen synthesis or breakdown therefore affect levels of [ Select ] ["glucose", "glycogen"] in the bloodstream and the amount of glycogen in the liver. This is exemplified by defects in [ Select ] ["glucose-6-phosphatase", "glycogen synthase"] , which is a deficit in breakdown and delivery, whereas mutations compromising [ Select ] ["glycogen synthase", "glycogen debranching enzyme"] result in a defect in synthesis, but defects in either enzyme produce [ Select ] ["hypoglycemia", "hypothermia"].
- Please briefly explain the ATP_modulated actomyosin cycle.In class, I mentioned that fructose is metabolized differently in the liver compared to glucose. Refer to the figure shown below to calculate the number ofATPs you would expect from the metabolism of fructose in the liver. Show your work! Fructokinase Fructose Fructose-1-P АТР ADP Aldolase B Dihydroxy- acetone phosphate Glyceraldehyde АТР Triose kinase Triose phosphate isomerase ADP 4 - Glyceraldehyde-3-P Glycolysis Руruvate Acetyl-CoA Fatty acids and triglyceridesUse your knowledge of fat metabolism. glycolysis, the TCA cycle, and axidative phosphorylation to determine how many molecules of ATP eauvalents are produced when glycerol undergoes biochemical combustion. Assume that each molecule of NADH produces 2.5 ATP and that each molecule of FADH2 produces 1.5 molecules of ATP during oxidative phosphorylation. Note that GTP is an ATp "equivalent." OA 14.5 OB. 17 OC. 19.5 OD. 20.5