One in 10,000 babies in the United States is born with phenylketonuria (PKU), a metabolic disorder caused by a recessive allele. What proportion of that human population is likely to be a carrier of the PKU

The most common allele of the β chain of hemoglobin in humans, ???,H⁢bA, has glutamic acid at the sixth position. Two different amino acid substitutions at the sixth position produce two variants, ???H⁢bS and ???,H⁢bC, of the sickle‑cell allele. The ???H⁢bS allele occurs when valine is substituted for glutamic acid, and the ???H⁢bC allele occurs when lysine is substituted for glutamic acid. To answer the question, refer to the amino acid table. Match the class of amino acid and the chemical property to each possible amino acid. Not all answers will be placed.

Please explain why Huntington’s Disease is a dominant allele, but its occurrence is very low in the population.

Choose a recent food recall or a restaurant food safety news story. Recent popular stories include the romaine lettuce recall, the Chipotle food safety outbreak, etc. Describe the cause of the incident and how they were able to trace it to the source. What illnesses did this lead to?

Alzheimer’s is a progressive neurological disorder resulting in dementia and memory loss that occurs in 10% of the US population older than 65. In the 1990s, several researchers showed evidence that the allele of a cholesterol precursor gene, APO E4, increased risk of developing the disorder compared to APO E2 or APO E3. This was especially pronounced if patients carried two alleles of APO E4. However, not all people with APO E4 develop the disorder and some without it will present with Alzheimer's nevertheless. This suggests other genes influence development of the disease. Current research has elucidated dozens of genes that interact with APO E4 pathways in hundreds of ways. As many as 27 of the interactions are epistatic, with some as dominant epistasis and some as recessive epistasis. In addition, some of the gene candidates for non-APO E4 Alzheimer’s have other relationships such as dominant, codominant or incomplete dominant. No reliable cure currently exists for Alzheimer’s…

Sickle cell anemia is a genetic disease most common in those of African ancestry that results from the mutation of a single basepair. This mutation results in a change to the hemoglobin protein. In this experiment, “S” will represent the normal allele and “s” thesickle allele. They are codominant alleles. Therefore, SS is normal, Ss is not fatal but mildly symptomatic, and ss is debilitating,painful, and often fatal. After hundreds or even thousands of generations, both alleles are still common in those of African ancestry. How would you explain this?

Sickle cell anemia is a genetically inherited autosomal recessive trait in which results in a condition that there are not enough healthy red blood cells to carry oxygen throughout the body due to the production of red blood cells that are sickle shaped. The frequency of the sickle cell condition is as high as 10% in Central Africa compared to 0.5% in the United States. Malaria is a disease caused by a parasite that infects healthy red blood cells and can lead to death. However, the parasite is not able to infect sickle cell red blood cells. Scientists claim that the higher frequency of sickle cell carriers is due to the presence of malaria. Provide reasoning to support the claim.