Of all the genes in the human genome, the ones withthe most characterized Alu insertions are those thatcause hemophilia, including several insertions in thefactor VIII and factor IX genes. Based on this fact, yourcolleague hypothesizes that the Alu element prefers toinsert into these genes. Do you agree? What other reason can you provide that also explains these data?

Why might the locations of introns and exons be the same in both alpha- and beta-hemoglobin genes?

the topic is Identification of Differentially Expressed Genes in Breast Cancer Using RNA-Seq write a method section of a scientific report for this topic. including the use of excel to get these result( will be included in the images) and also this website https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE216238

You are studying mutations in a bacterial gene thatcodes for an enzyme whose amino acid sequence isknown. In the wild-type protein, proline is the fifthamino acid from the amino terminal end. In one ofyour mutants with nonfunctional enzyme, you find aserine at position number 5. You subject this mutant tofurther mutagenesis and recover three different strains.Strain A has a proline at position number 5 and actsjust like a wild-type strain. Strain B has tryptophanat position number 5 and also acts like wild type.Strain C has no detectable enzyme function at anytemperature, and you can’t recover any protein thatresembles the enzyme. You mutagenize strain C andrecover a strain (C-1) that has enzyme function. Thesecond mutation in C-1 that is responsible for therecovery of enzyme function does not map at theenzyme locus.a. What is the nucleotide sequence in both strands ofthe wild-type gene at this location?b. Why does strain B have a wild-type phenotype? Whydoes the original mutant with…