Human Anatomy & Physiology (11th Edition)
11th Edition
ISBN: 9780134580999
Author: Elaine N. Marieb, Katja N. Hoehn
Publisher: PEARSON
expand_more
expand_more
format_list_bulleted
Concept explainers
Question
36/ in human, the antibiotic amoxicillin used to treat certain bacterial infections. a. does the antibiotic inhibit human enzymes?
b. Why does the antibiotic kill bacteria but not humans?
c. Is amoxicillin a reversible or irreversible inhibitor?
Expert Solution
This question has been solved!
Explore an expertly crafted, step-by-step solution for a thorough understanding of key concepts.
This is a popular solution
Trending nowThis is a popular solution!
Step by stepSolved in 2 steps
Knowledge Booster
Learn more about
Need a deep-dive on the concept behind this application? Look no further. Learn more about this topic, biology and related others by exploring similar questions and additional content below.Similar questions
- The purified OXA-M290 enzyme can now be tested to determine which β-lactamase inhibitor is most effective. This inhibitor could be prescribed in combination with a β-lactam antibiotic to treat the infection caused by the E. coli KGH1 strain. Before testing inhibitors against OXA-M290, the kinetic activity of this enzyme must first be measured. The activity of OXA-M290 is measured using nitrocefin, a chromogenic β-lactam antibiotic. When nitrocefin is hydrolyzed by a β-lactamase, it changes from yellow to red in colour. The nitrocefin hydrolysis product has an extinction coefficient of 20,500 M-1 cm-1 at 486 nm. The hydrolysis of 60 μM nitrocefin by 1 nM OXA-M290 is monitored using a microplate reader. The absorbance of the wells in the plate is measured at 486 nm every 30 seconds. This experiment is carried out with three replicates, generating the following data: Time (min) Absorbance of Replicate 1 Absorbance of Replicate 2 Absorbance of Replicate 3 0.5 0.0984…arrow_forwardWhy are protein synthesis inhibitors typically broad spectrum? What might prevent a protein synthesis inhibitor from being broad-spectrum?arrow_forwardcomplete solutions pleasearrow_forward
- Draw the mechanism of action of an HIV protease. Label the substrate, the intermediates, and the products. Indicate each type of catalysis that occurs throughout the mechanism..arrow_forwardBIOCHEMISTRY Which methodologies can be used to detect the expression of a given protein? Please provide pros and cons of each mentioned approach.arrow_forwardExplain the mode of action of transcription inhibitor metarrestin. Explain why transcription inhibitor is a good anticancer drug.arrow_forward
- Some cancer researchers have proposed using a-amanitin in cancer therapy. How might a-amanitin be used in the treatment of cancer?arrow_forward. You need to prepare 500 μL of a 250 µg/mL bovine gamma globulin solution, for one of your protein standards in the Bradford assay. The available bovine gamma globulin in the lab is in the form of a 2 mg/mL stock solution, and it can be diluted with deionized water. Describe or show below how you would create your desired 250 µg/mL solution.arrow_forwardKk.31.arrow_forward
- a. A single mutation in the riboswitch’s sequence changes the ligand binding specificity from guanine toadenine. Predict what single mutation could be made in the guanine-responsive riboswitch sequenceto convert it to an adenine-responsive riboswitch. Justify your answer b. Could a DNA molecule with the same nucleotide sequence as the guanine-responsive riboswitch bindguanine in a similar manner as the RNA-based molecule? Explainarrow_forward61. Greene and colleagues studied Zonosemata flies to see if their wing displays and markings deterred spider predators. They set up five experimental groups, as shown below: A в D E Treatment Zonosemata untreated Zonosemata Zonosemata with housefly wings Housefly with Zonosemata wings Housefly untreated with own wings cut and reglued What is the purpose of group D in the preceding figure? a. To examine the effects of the markings alone. b. To examine the effects another prey item. c. To examine the effects of the behavior alone. d. To examine the combined effects of the markings and behavior. To control for the operation of removing the wings. 62. You are asked to determine plant species diversity in a prairie patch. To determine how many samples to take you construct a a. species-area; the curve intercepts the x-axis b. species-area; the curve reaches an asymptote c. species-area; the curve displays damped oscillations d. rank-abundance; the curve intercepts the x-axis e.…arrow_forwardMolecular biology, please explain in detailsarrow_forward
arrow_back_ios
arrow_forward_ios
Recommended textbooks for you
- Human Anatomy & Physiology (11th Edition)BiologyISBN:9780134580999Author:Elaine N. Marieb, Katja N. HoehnPublisher:PEARSONBiology 2eBiologyISBN:9781947172517Author:Matthew Douglas, Jung Choi, Mary Ann ClarkPublisher:OpenStaxAnatomy & PhysiologyBiologyISBN:9781259398629Author:McKinley, Michael P., O'loughlin, Valerie Dean, Bidle, Theresa StouterPublisher:Mcgraw Hill Education,
- Molecular Biology of the Cell (Sixth Edition)BiologyISBN:9780815344322Author:Bruce Alberts, Alexander D. Johnson, Julian Lewis, David Morgan, Martin Raff, Keith Roberts, Peter WalterPublisher:W. W. Norton & CompanyLaboratory Manual For Human Anatomy & PhysiologyBiologyISBN:9781260159363Author:Martin, Terry R., Prentice-craver, CynthiaPublisher:McGraw-Hill Publishing Co.Inquiry Into Life (16th Edition)BiologyISBN:9781260231700Author:Sylvia S. Mader, Michael WindelspechtPublisher:McGraw Hill Education
Human Anatomy & Physiology (11th Edition)
Biology
ISBN:9780134580999
Author:Elaine N. Marieb, Katja N. Hoehn
Publisher:PEARSON
Biology 2e
Biology
ISBN:9781947172517
Author:Matthew Douglas, Jung Choi, Mary Ann Clark
Publisher:OpenStax
Anatomy & Physiology
Biology
ISBN:9781259398629
Author:McKinley, Michael P., O'loughlin, Valerie Dean, Bidle, Theresa Stouter
Publisher:Mcgraw Hill Education,
Molecular Biology of the Cell (Sixth Edition)
Biology
ISBN:9780815344322
Author:Bruce Alberts, Alexander D. Johnson, Julian Lewis, David Morgan, Martin Raff, Keith Roberts, Peter Walter
Publisher:W. W. Norton & Company
Laboratory Manual For Human Anatomy & Physiology
Biology
ISBN:9781260159363
Author:Martin, Terry R., Prentice-craver, Cynthia
Publisher:McGraw-Hill Publishing Co.
Inquiry Into Life (16th Edition)
Biology
ISBN:9781260231700
Author:Sylvia S. Mader, Michael Windelspecht
Publisher:McGraw Hill Education